Gene Symbol | FAM132A |
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Entrez Gene | 388581 |
Alt Symbol | C1QDC2, C1QTNF12, CTRP12 |
Species | Human |
Gene Type | protein-coding |
Description | family with sequence similarity 132, member A |
Other Description | C1q domain containing 2|C1q/TNF-related protein 12|adipolin|adipose-derived insulin-sensitizing factor|complement C1q tumor necrosis factor-related protein 12|protein FAM132A |
Swissprots | Q5T7M4 Q5EBL5 |
Accessions | Q5T7M4 AW873053 BC089443 AAH89443 XM_011541435 XP_011539737 XM_011541436 XP_011539738 XM_011541437 XP_011539739 NM_001014980 NP_001014980 |
Function | Insulin-sensitizing adipocyte-secreted protein (adipokine) that regulates glucose metabolism in liver and adipose tissue. Promotes glucose uptake in adipocytes and suppresses de novo glucose production in hepatocytes via the PI3K-Akt signaling pathway. Administration lead to reduction of blood glucose. Able to attenuate inflammation in fat tissue (By similarity). {ECO:0000250}. |
Subcellular Location | Adipolin fCTRP12: Secreted. |
Tissue Specificity | Predominantly expressed by adipose tissues. {ECO:0000269|PubMed:22275362}. |
FAM132A Antibody Blocking Peptide - LS-E24991 from LifeSpan Bioscience
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FAM132A-Antibody-Center-Blocking-peptide - BP12685c from Abgent, a WuXi AppTec company
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Human FAM132A Protein - abx066488 from Abbexa
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Family With Sequence Similarity 132 Member A - 20-9642 from ARP American Research Products
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Recombinant Family With Sequence Similarity 132, Member A (FAM132A) - RPV122Hu01 from Uscn Life Science Inc.
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Recombinant Family With Sequence Similarity 132, Member A (FAM132A) - RPV122Hu02 from Uscn Life Science Inc.
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Recombinant Family With Sequence Similarity 132, Member A (FAM132A) - RPV122Hu01 from Cloud-clone
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Recombinant Family With Sequence Similarity 132, Member A (FAM132A) - RPV122Hu02 from Cloud-clone
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Recombinant Human Protein FAM132A(FAM132A) - CSB-YP713130HU CSB-EP713130HU CSB-BP713130HU CSB-MP713130HU from Cusabio
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Family With Sequence Similarity 132, Member A (FAM132A) - RPU141339 from Biomatik
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Adipolin/FAM132A Recombinant Protein Antigen - NBP1-90700PEP from Novus Biologicals
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FAM132A Peptide, Human - M34GP05264H from Creative Peptides
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Family With Sequence Similarity 132, Member A (FAM132A), Recombinant Protein - MBS2011316 from MyBioSource
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Recombinant Family With Sequence Similarity 132, Member A (FAM132A) - RPU41339 from Biomatik
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FAM132A Recombinant Protein (OPCD03067) - OPCD03067 from Aviva Systems Biology
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Protein FAM132A (FAM132A), Recombinant Protein - MBS1442121 from MyBioSource
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Recombinant Family With Sequence Similarity 132, Member A (FAM132A) - RPU55415 from Biomatik
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