BCL9L

Gene Symbol BCL9L
Entrez Gene 283149
Alt Symbol BCL9-2, DLNB11
Species Human
Gene Type protein-coding
Description B-cell CLL/lymphoma 9-like
Other Description B-cell CLL/lymphoma 9-like protein|B-cell lymphoma 9-like protein|BCL9-like protein|nuclear co-factor of beta-catenin signalling|protein BCL9-2
Swissprots Q6ZWK2 Q86UU0 A1A4C1 Q67FY1 Q6ZWJ0
Accessions EAW67418 Q86UU0 AB094091 BAC76045 AK122650 BAC85500 AK122882 BAC85512 AY296059 AAQ62697 BC033257 AAH33257 BC156197 AAI56198 XM_005271511 XP_005271568 XM_005271512 XP_005271569 XM_005271513 XP_005271570 XM_006718815 XP_006718878 XM_011542756 XP_011541058 NM_182557 NP_872363
Function Transcriptional regulator that acts as an activator. Promotes beta-catenin transcriptional activity. Plays a role in tumorigenesis. Enhances the neoplastic transforming activity of CTNNB1 (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000269|PubMed:17129358, ECO:0000269|PubMed:17309600}.
Tissue Specificity Expressed in breast, ductal and invasive ductal carcinomas of the breast, sporadic colorectal adenomas and carcinomas (at protein level). Expressed in fetal brain. Expressed in lung, amygdala, eye, prostate, pancreatic and prostate cancers, head and neck tumors and embryonal tumor. {ECO:0000269|PubMed:12964048, ECO:0000269|PubMed:17129358, ECO:0000269|PubMed:17309600}.

Phospho-BCL9L (Ser915) Antibody - 13325 from Cell Signaling Technology

Prices $287.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from MCF7 cells, untreated (-) or treated with TPA #4174 (200 nM, 30 min; +), using Phospho-BCL9L (Ser915) Antibody (upper) or β-Actin (D6A8) Rabbit mAb #8457 (lower).

Bcl-9L (H-225) - sc-292150 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Bcl-9L (H-225): sc-292150. Western blot analysis of Bcl-9L expression in RAW 264.7 (A) and SP2/0 (B) whole cell lysates and mouse testis tissue extract (C).

Bcl-9L (Q-18) - sc-103403 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-BCL9L antibody - ab113110 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-BCL9L antibody (ab113110) at 1 µg/mlLane 1 : HeLa cell lysateLane 2 : HeLa cell lysate with Blocking peptide

Anti-BCL9L Antibody (aa147-176, AP) - LS-C233099 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BCL9L Antibody (aa147-176, APC) - LS-C233098 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BCL9L Antibody (aa147-176, FITC) - LS-C233101 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BCL9L Antibody (aa147-176, Biotin) - LS-C233100 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BCL9L Antibody (aa147-176, PE) - LS-C233102 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BCL9L Antibody (aa147-176) - LS-C157580 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
BCL9L Antibody western blot of human placenta tissue lysates (35 ug/lane). The BCL9L antibody detected the BCL9L protein (arrow).

Anti-BCL9L Antibody (aa147-176, Azide-free, HRP) - LS-C249513 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BCL9L Antibody (aa606-715) - LS-C306533 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-BCL9L Antibody (aa147-176) - LS-C319815 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BCL9L Antibody (aa525-575) - LS-C289852 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human BCL9L by Western Blot and Immunoprecipitation. Samples: Whole cell lysate from HeLa (15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded) and 293T (T; 50 ug) cells. Antibodies: Affinity purified rabbit anti-BCL9L antibody used for WB at 0.1 ug/ml (A) and 1 ug/ml (B) and used for IP at 6 ug/mg lysate. BCL9L was also immunoprecipitated by rabbit anti-BCL9L antibody BL11259, which recognizes an upstream epitope. Detection: Chemiluminescence with exposure times of 3 minutes (A and B).

Anti-BCL9L Antibody (N-Terminus) - LS-C144336 from LifeSpan Bioscience

Prices $345.00, $1,035.00
Sizes 100 µg, 500 µg
Host Rabbit
Clonality Polyclonal
Immunocytochemistry of Bcl9L in HeLa cells with Bcl9L antibody at 10 ug/ml.

BCL9-2 Antibody [Unconjugated] - AF4967 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep
Clonality Polyclonal
Western blot shows lysates of A172 human glioblastoma cell line and MCF‑7 human breast cancer cell line. PVDF membrane was probed with 1 µg/mL of Human Bcl9‑2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4967) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). A specific band was detected for Bcl9‑2 at approximately 190 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

BCL9-2 Antibody - NBP1-76542 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

BCL9-2 Antibody - NBP2-14350 from Novus Biologicals

Prices $129.00, $419.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: BCL9-2 Antibody [NBP2-14350] - Analysis in human cell line CACO-2.

BCL9-2 Antibody - NBP1-71907 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: BCL9-2 Antibody [NBP1-71907] - Whole cell lysate from HeLa (15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) and 293T (T; 50 mcg) cells. Affinity purified rabbit anti-BCL9L antibody used for WB at 0.1 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 6 mcg/mg lysate. BCL9L was also immunoprecipitated by another rabbit anti-BCL9L antibody, which recognizes an upstream epitope.

BCL9-2 Antibody (5E8) - H00283149-M01 from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone 5E8

Anti-BCL9L antibody produced in rabbit - HPA049370 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-BCL9L:<B>Cat. No. HPA049370</B>: Immunohistochemical staining of human breast shows moderate nuclear positivity in glandular cells.

Monoclonal Anti-BCL9L antibody produced in mouse - WH0283149M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5E8

ANTI-BCL9L (N-TERM) antibody produced in rabbit - SAB1306902 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-BCL9L (N-term): <B>Cat. No. SAB1306902</B>: BCL9L Antibody (N-term) western blot analysis in Human placenta tissue lysates (35 μg/lane).

Anti-BCL9L antibody produced in rabbit - SAB3500665 from Sigma-Aldrich

Prices $341.00
Sizes 100 µg
Host Rabbit
<B>Immunoblotting</B><BR/>Anti-BCL9L; <B>Cat. No. SAB3500665</B>; Western blot analysis of Bcl9L in HeLa cell lysate with Bcl9L antibody at 1 μ/mL in (A) the absence and (B) the presence of blocking peptide.

BCL9L-AntibodyN-term - AP19875a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
BCL9L Antibody (N-term) (Cat. #AP19875a) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the BCL9L antibody detected the BCL9L protein (arrow).
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