Pde3b

Gene Symbol Pde3b
Entrez Gene 18576
Alt Symbol 9830102A01Rik, AI847709
Species Mouse
Gene Type protein-coding
Description phosphodiesterase 3B, cGMP-inhibited
Other Description CGI-PDE B|CGIPDE1|cGMP-inhibited 3',5'-cyclic phosphodiesterase B|cyclic GMP-inhibited phosphodiesterase B
Swissprots Q61409 Q9Z1J9 Q8CIX5
Accessions EDL17069 EDL17070 EDL17071 Q61409 AF547435 AAN52086 AJ132271 CAA10639 AK036412 AK044183 AK142889 BAE25219 AV270888 BB627812 BB663310 BC169298 BC169299 BC169300 BU613166 BY745829 CJ058099 CJ299201 X95521 CAA64775 XM_006507438 XP_006507501 XM_006507439 XP_006507502 NM_011055 NP_035185
Function Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6 assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which is involved in angiogenesis (By similarity). {ECO:0000250}.
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity Abundant in adipose tissues.
Top Pathways Insulin signaling pathway, Progesterone-mediated oocyte maturation, Morphine addiction, cGMP-PKG signaling pathway, cAMP signaling pathway

PDE3B CRISPR/Cas9 KO Plasmid (m) - sc-422159 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

PDE3B HDR Plasmid (m) - sc-422159-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

PDE3B Double Nickase Plasmid (m) - sc-422159-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

PDE3B Double Nickase Plasmid (m2) - sc-422159-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

PDE3B CRISPR Activation Plasmid (m) - sc-422159-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

PDE3B CRISPR Activation Plasmid (m2) - sc-422159-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

PDE3B Lentiviral Activation Particles (m) - sc-422159-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

PDE3B Lentiviral Activation Particles (m2) - sc-422159-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

PDE3B siRNA (m) - sc-41595 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

PDE3B shRNA Plasmid (m) - sc-41595-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

PDE3B shRNA (m) Lentiviral Particles - sc-41595-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU007721 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN38456 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND38456 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PDE3B siRNA (Mouse) - CRM2994 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse PDE3B (NM_011055.2) - SHH372420 from Creative biogene

Category siRNA
Species Reactivities Mouse

shRNA set against Mouse Pde3b(NM_011055.2) - SHR099912 from Creative biogene

Category siRNA
Species Reactivities Mouse

Mouse PDE3B siRNA - orb282470 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

PDE3B shRNA Plasmid (Mouse) - CHM2994 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse

PDE3B miRNA 3'UTR clone - MiUTR1M-09045 from Creative biogene

Species Reactivities Mouse
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