Gene Symbol | GNG2 |
---|---|
Entrez Gene | 54331 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | guanine nucleotide binding protein (G protein), gamma 2 |
Other Description | g gamma-I|guanine nucleotide binding protein gamma 2|guanine nucleotide-binding protein G(I)/G(O) gamma-2 subunit|guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 |
Swissprots | Q5JPE2 Q6P9A9 P59768 |
Accessions | EAW65663 EAW65664 EAW65665 P59768 AB074180 AF130106 AAG35531 AF493870 AAM12584 AK001024 AK026424 AK026425 AK092371 AK307171 AK311334 AL832878 CAI46198 BC020774 AAH20774 BC041446 BC060856 AAH60856 BE245271 BQ025819 DA226565 DA322879 DA785895 DC318652 XM_006720173 XP_006720236 XM_011536845 XP_011535147 XM_011536846 XP_011535148 NM_001243773 NP_001230702 NM_001243774 NP_001230703 NM_053064 NP_444292 |
Function | Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. |
Tissue Specificity | Expressed in fetal tissues, including testis, adrenal gland, brain, white blood cells and brain. {ECO:0000269|PubMed:10833460}. |
Top Pathways | Dopaminergic synapse, Morphine addiction, Glutamatergic synapse, PI3K-Akt signaling pathway, GABAergic synapse |
G γ 2 CRISPR/Cas9 KO Plasmid (h) - sc-416665 from Santa Cruz Biotechnology
|
||||||||
G γ 2 HDR Plasmid (h) - sc-416665-HDR from Santa Cruz Biotechnology
|
||||||||
G γ 2 Double Nickase Plasmid (h) - sc-416665-NIC from Santa Cruz Biotechnology
|
||||||||
G γ 2 Double Nickase Plasmid (h2) - sc-416665-NIC-2 from Santa Cruz Biotechnology
|
||||||||
G γ 2 CRISPR Activation Plasmid (h) - sc-416665-ACT from Santa Cruz Biotechnology
|
||||||||
G γ 2 CRISPR Activation Plasmid (h2) - sc-416665-ACT-2 from Santa Cruz Biotechnology
|
||||||||
G γ 2 Lentiviral Activation Particles (h) - sc-416665-LAC from Santa Cruz Biotechnology
|
||||||||
G γ 2 Lentiviral Activation Particles (h2) - sc-416665-LAC-2 from Santa Cruz Biotechnology
|
||||||||
G γ 2 siRNA (h) - sc-41774 from Santa Cruz Biotechnology
|
||||||||
G γ 2 shRNA Plasmid (h) - sc-41774-SH from Santa Cruz Biotechnology
|
||||||||
G γ 2 shRNA (h) Lentiviral Particles - sc-41774-V from Santa Cruz Biotechnology
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN9427 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9427 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR13834 from Sigma-Aldrich
|
||||||||
GNG2 siRNA (Human) - CRJ0038 from Cohesion Biosciences
|
||||||||
GNG2 RNAi - H00054331-R01 from Novus Biologicals
|
||||||||
GNG2 - MBS8240136 from MyBioSource
|
||||||||
shRNA set against Human GNG2 (NM_053064.4) - SHH304886 from Creative biogene
|
||||||||
GNG2 shRNA Plasmid (Human) - CHJ0038 from Cohesion Biosciences
|