| Gene Symbol | FIGNL1 |
|---|---|
| Entrez Gene | 63979 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | fidgetin-like 1 |
| Other Description | fidgetin-like protein 1 |
| Swissprots | Q9H8P1 Q6PIW4 Q86V18 Q8ND59 Q9H917 D3DVM6 |
| Accessions | AAS01996 EAL23899 EAW60975 EAW60976 Q6PIW4 AK023142 BAB14426 AK023411 BAB14567 AK027537 BAG51338 AK308136 AL834387 CAD39050 BC027856 BC051867 AAH51867 BU166325 BU741583 BX342197 DA114757 DA121143 DA121992 DA433617 DA798223 DA812999 DB067077 EU832584 ACE86986 XM_005271783 XP_005271840 XM_011515469 XP_011513771 XM_011515470 XP_011513772 XM_011515471 XP_011513773 XM_011515472 XP_011513774 NM_001042762 NP_001036227 NM_001287492 NP_001274421 NM_001287493 NP_001274422 NM_001287494 NP_001274423 NM_001287495 NP_001274424 NM_001287496 NP_001274425 NM_022116 NP_071399 |
| Function | Involved in DNA double-strand break (DBS) repair via homologous recombination (HR). Recruited at DSB sites independently of BRCA2, RAD51 and RAD51 paralogs in a H2AX- dependent manner. May regulate osteoblast proliferation and differentiation. {ECO:0000269|PubMed:23754376}. |
| Subcellular Location | Nucleus {ECO:0000269|PubMed:23754376}. Note=Together with RAD51 and a subset of H2A histone proteins, redistributed in discrete nuclear DNA damage-induced foci after ionizing radiation (IR) treatment. |
fidgetin-like 1, ELISA Kit - MBS9331201 from MyBioSource
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Human FIGNL1 ELISA Kit - E015144 from Biobool
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