CYP51A1

Gene Symbol CYP51A1
Entrez Gene 1595
Alt Symbol CP51, CYP51, CYPL1, LDM, P450-14DM, P450L1
Species Human
Gene Type protein-coding
Description cytochrome P450, family 51, subfamily A, polypeptide 1
Other Description CYPLI|cytochrome P450 51A1|cytochrome P450, 51 (lanosterol 14-alpha-demethylase)|cytochrome P450-14DM|cytochrome P45014DM|cytochrome P450LI|lanosterol 14-alpha demethylase|lanosterol 14-alpha-demethylase|sterol 14-alpha demethylase
Swissprots Q99868 B4DJ55 O00772 B2RAI4 Q16850 Q8N1A8 A4D1F8 O00770 Q16784
Accessions AAB46356 AAC50951 EAL24154 EAW76858 EAW76859 Q16850 AK295932 BAG58717 AK314205 BAG36881 BC018429 AAH18429 BC032322 AAH32322 D55653 BAA09512 DA349400 DC376300 DQ891311 ABM82237 DQ894495 ABM85421 U23942 AAB39951 NM_000786 NP_000777 NM_001146152 NP_001139624
Function Catalyzes C14-demethylation of lanosterol; it transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol. {ECO:0000269|PubMed:20149798}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000305}. Microsome membrane {ECO:0000305}.
Tissue Specificity Ubiquitously expressed with highest levels in testis, ovary, adrenal, prostate, liver, kidney and lung. {ECO:0000269|PubMed:8619637}.
Top Pathways Steroid biosynthesis

Human CYP51A1 protein fragment - ab158260 from Abcam

Category Protein
Source Wheat germ
Species Human
ab158260 on a 12.5% SDS-PAGE stained with Coomassie Blue.

CYP51A1 / CYP51 Antibody Blocking Peptide - LS-E22027 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

CYP51A1 / CYP51 Antibody Blocking Peptide - LS-E9826 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

CYP51A1 / CYP51 Antibody Blocking Peptide - LS-E9827 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human CYP51A1 Protein - H00001595-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

CYP51A1-Antibody-Center-Blocking-Peptide - BP8874c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

CYP51A1-Antibody-C-term-Blocking-Peptide - BP8874b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

CYP51A1 Blocking Peptide - 33R-9393 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

CYP51A1 - H00001595-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

CYP51A1 - H00001595-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

CYP51A1 fusion protein - Ag4235 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

CYP51A1 fusion protein - Ag6850 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

Recombinant Human CYP51A1, GST-tagged - CYP51A1-11794H from Creative Biomart

Category Protein
Source E.coli
Species Human

Recombinant Lanosterol 14-alpha demethylase(cyp51) - CSB-YP006459MVZ CSB-EP006459MVZ CSB-BP006459MVZ CSB-MP006459MVZ from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Mycobacterium

Recombinant Lanosterol 14-alpha demethylase(cyp51) - CSB-YP006459MVH CSB-EP006459MVH CSB-BP006459MVH CSB-MP006459MVH from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Mycobacterium

CYP51A1 - TP307078 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
CYP51A1

CYP51A1 Recombinant Protein Antigen - NBP2-48793PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E. coli
Species Human

CYP51A1 Recombinant Protein Antigen - NBP2-48733PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E. coli
Species Human

CYP51A1 Peptide, Human - M34GP03987H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Lanosterol 14-alpha demethylase (cyp51), Recombinant Protein - MBS1473296 from MyBioSource

Category Protein
Prices $1,230.00, $1,230.00, $1,450.00, $1,450.00, $2,000.00, $2,000.00, $2,465.00, $2,465.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Mycobacterium

Lanosterol 14-alpha demethylase (cyp51), Recombinant Protein - MBS1194133 from MyBioSource

Category Protein
Prices $1,230.00, $1,230.00, $1,450.00, $1,450.00, $2,000.00, $2,000.00, $2,460.00, $2,460.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Mycobacterium

Lanosterol 14-alpha demethylase (cyp51), Recombinant Protein - MBS1202641 from MyBioSource

Category Protein
Prices $1,230.00, $1,230.00, $1,450.00, $1,450.00, $2,000.00, $2,000.00, $2,460.00, $2,460.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Mycobacterium

Lanosterol 14-alpha demethylase (CYP51A1), Recombinant Protein - MBS7013474 from MyBioSource

Category Protein
Prices $1,300.00, $2,290.00, $3,495.00
Sizes 10 µg, 50 µg, 100 µg
Source Cell Free Expression
Species Human

Lanosterol 14-alpha demethylase (CYP51A1), Recombinant Protein - MBS7013478 from MyBioSource

Category Protein
Prices $1,300.00, $2,290.00, $3,495.00
Sizes 10 µg, 50 µg, 100 µg
Source Cell Free Expression
Species Orangutan

Lanosterol 14-alpha demethylase (ERG11), Recombinant Protein - MBS7053422 from MyBioSource

Category Protein
Prices $1,735.00, $1,890.00, $2,050.00, $2,165.00, $2,360.00, $2,390.00, $2,705.00, $2,960.00, $3,425.00, $4,275.00
Sizes 50 µg (Baculovirus), 500 µg (E-Coli), 500 µg (Yeast), 100 µg (Baculovirus), 1 mg (E-Coli), 50 µg (Mammalian-Cell), 1 mg (Yeast), 100 µg (Mammalian-Cell), 500 µg (Baculovirus), 1 mg (Baculovirus)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
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