Gene Symbol | PTP4A1 |
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Entrez Gene | 7803 |
Alt Symbol | HH72, PRL-1, PRL1, PTP(CAAX1), PTPCAAX1 |
Species | Human |
Gene Type | protein-coding |
Description | protein tyrosine phosphatase type IVA, member 1 |
Other Description | protein tyrosine phosphatase type IVA 1|protein tyrosine phosphatase type IVA protein 1|protein-tyrosine phosphatase 4a1|protein-tyrosine phosphatase of regenerating liver 1 |
Swissprots | Q49A54 B2R6C8 O00648 Q93096 |
Accessions | AAC39836 EAW88494 EAW88495 Q93096 AB451314 BAG70128 AB451444 BAG70258 AJ420505 AK312526 BAG35425 AW136267 BC023975 AAH23975 BC045571 AAH45571 BF436021 BG717869 BI222469 BP264358 BU632706 CA427371 CR749458 CAH18292 DQ890715 ABM81641 DQ893895 ABM84821 EU831599 ACE87199 EU831686 ACE86520 U48296 AAB40597 U69701 AAB09080 XM_011536111 XP_011534413 XM_011536112 XP_011534414 NM_003463 NP_003454 |
Function | Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. May play a role in the development and maintenance of differentiating epithelial tissues. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. {ECO:0000269|PubMed:12235145, ECO:0000269|PubMed:12782572, ECO:0000269|PubMed:14643450}. |
Subcellular Location | Cell membrane. Early endosome. Endoplasmic reticulum. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Note=And mitotic spindle. |
Tissue Specificity | Expressed in bone marrow, lymph nodes, T lymphocytes, spleen, thymus and tonsil. Overexpressed in tumor cell lines. {ECO:0000269|PubMed:10940933, ECO:0000269|PubMed:12235145}. |
Active human PTP4A1 full length protein - ab157013 from Abcam
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Human PTP4A1 full length protein - ab101827 from Abcam
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Human PTP4A1 full length protein - ab87873 from Abcam
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Human PTP4A1 full length protein - ab42567 from Abcam
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PTP4A1 peptide - ab45609 from Abcam
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PTP4A1 / PRL-1 Antibody Blocking Peptide - LS-E4575 from LifeSpan Bioscience
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PTP4A1 / PRL-1 Antibody Blocking Peptide - LS-E25758 from LifeSpan Bioscience
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PTP4A1 / PRL-1 Antibody Blocking Peptide - LS-E25268 from LifeSpan Bioscience
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PTP4A1 Recombinant Protein - H00007803-P01 from Novus Biologicals
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Recombinant Human PTP4A1 Protein - NBP1-50946 from Novus Biologicals
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PTP4A1-Antibody-C-term-Blocking-Peptide - BP16923b from Abgent, a WuXi AppTec company
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PRL1/PTP4A1 blocking peptide - GTX89677-PEP from GeneTex
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PTP4A1/PRL-1 blocking peptide - GTX89969-PEP from GeneTex
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Recombinant Human PRL-1/PTP4A1, CF - 8490-PT-050 from R&D Systems
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PTP4A1 Protein (OPPA02609) - OPPA02609 from Aviva Systems Biology
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Human PTP4A1 protein - orb169120 from Biorbyt
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PTP4A1 protein (His tag) - 80R-1621 from Fitzgerald
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PTP4A1 Peptide - AC21-0096-P from Abcore
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PTP4A1 Peptide - AC21-0587-P from Abcore
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PTP4A1 / PRL1 (2-173, Active Enzyme) - AR00167PU-N from Acris Antibodies
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PTP4A1 / PRL1 (1-170, His-tag) - AR09802PU-L from Acris Antibodies
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PTP4A1 / PRL1 (1-170, His-tag) - AR09802PU-N from Acris Antibodies
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PTP4A1 / PRL1 - H00007803-P01-10 from Acris Antibodies
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PTP4A1 / PRL1 - H00007803-P01-25 from Acris Antibodies
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Protein Tyrosine Phosphatase Type IVA Member 1, Human Recombinant - 228-12204-1 from RayBiotech
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