| Gene Symbol |
ADAM19
|
| Entrez Gene |
8728
|
| Alt Symbol |
FKSG34, MADDAM, MLTNB
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ADAM metallopeptidase domain 19
|
| Other Description |
ADAM 19|a disintegrin and metalloproteinase domain 19 (meltrin beta)|disintegrin and metalloproteinase domain-containing protein 19|meltrin-beta|metalloprotease and disintegrin dendritic antigen marker|metalloprotease-disintegrin meltrin beta
|
| Swissprots |
Q9UHP2 Q9BZL5 Q9H013
|
| Accessions |
EAW61595 EAW61596 EAW61597 EAW61598 Q9H013 AF134707 AAF22162 AF311317 AAK07852 AF326918 AAG50282 AK091464 BAG52367 AK093535 AK308182 AL049415 BC024214 AAH24214 BC033132 AAH33132 BC140323 AAI40324 HY088077 Y13786 CAC20585 XM_005266003 XP_005266060 XM_011534680 XP_011532982 XM_011534681 XP_011532983 XM_011534682 XP_011532984 NM_033274 NP_150377 NM_023038
|
| Function |
Participates in the proteolytic processing of beta-type neuregulin isoforms which are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell. Also cleaves alpha-2 macroglobulin. May be involved in osteoblast differentiation and/or osteoblast activity in bone (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Membrane; Single-pass type I membrane protein.
|
| Tissue Specificity |
Expressed in many normal organ tissues and several cancer cell lines.
|
![Western Blot: ADAM19 Overexpression Lysate (Adult Normal) [NBL1-07307] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ADAM19.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1354_ADAM19%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-07307-img0002.jpg)