Notch3

Gene Symbol Notch3
Entrez Gene 18131
Alt Symbol AW229011, N3, hpbk
Species Mouse
Gene Type protein-coding
Description notch 3
Other Description Notch gene homolog 3|neurogenic locus notch homolog protein 3
Swissprots Q61982
Accessions EDL40331 Q61982 BC172738 AAI72738 X74760 CAA52776 NM_008716 NP_032742
Function Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity). May play a role during CNS development. {ECO:0000250}.
Subcellular Location Cell membrane; Single-pass type I membrane protein.
Tissue Specificity Proliferating neuroepithelium.
Top Pathways Notch signaling pathway, MicroRNAs in cancer, Dorso-ventral axis formation

Notch 3 CRISPR/Cas9 KO Plasmid (m) - sc-421933 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Notch 3 HDR Plasmid (m) - sc-421933-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Notch 3 Double Nickase Plasmid (m) - sc-421933-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Notch 3 Double Nickase Plasmid (m2) - sc-421933-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Notch 3 CRISPR Activation Plasmid (m) - sc-421933-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Notch 3 CRISPR Activation Plasmid (m2) - sc-421933-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Notch 3 Lentiviral Activation Particles (m) - sc-421933-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Notch 3 Lentiviral Activation Particles (m2) - sc-421933-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Notch 3 siRNA (m) - sc-37136 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

Notch 3 shRNA Plasmid (m) - sc-37136-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

Notch 3 shRNA (m) Lentiviral Particles - sc-37136-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU038311 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN36582 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND36582 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

NOTCH3 siRNA (Mouse) - CRM2811 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse NOTCH3 (NM_008716.2) - SHH353848 from Creative biogene

Category siRNA
Species Reactivities Mouse

shRNA set against Mouse Notch3(NM_008716.2) - SHR008664 from Creative biogene

Category siRNA
Species Reactivities Mouse

Notch 3 CRISPR/Cas9 KO Plasmid (m2) - sc-421933-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Notch 3 HDR Plasmid (m2) - sc-421933-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

NOTCH3 shRNA Plasmid (Mouse) - CHM2811 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse

NOTCH3 miRNA 3'UTR clone - MiUTR1M-07750 from Creative biogene

Species Reactivities Mouse
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