SDCBP

Gene Symbol SDCBP
Entrez Gene 6386
Alt Symbol MDA-9, MDA9, ST1, SYCL, TACIP18
Species Human
Gene Type protein-coding
Description syndecan binding protein (syntenin)
Other Description melanoma differentiation associated protein-9|melanoma differentiation-associated protein 9|pro-TGF-alpha cytoplasmic domain-interacting protein 18|scaffold protein Pbp1|syndecan-binding protein 1|syntenin-1
Swissprots B2R5Q7 B7ZLN2 O43391 O00560 O00173 B4DUH3 Q14CP2
Accessions EAW86812 EAW86813 EAW86814 EAW86815 EAW86816 O00560 AF000652 AAB97144 AF006636 AAC52050 AK128645 AK295198 BAG58197 AK298697 BAG60855 AK300647 BAG62335 AK312274 BAG35204 BC013254 BC113674 AAI13675 BC113676 AAI13677 BC143915 AAI43916 BC143916 AAI43917 BG111210 BG772269 BU160865 HQ258156 ADR82910 U83463 AAB51246 XM_011517571 XP_011515873 NM_001007067 NP_001007068 NM_001007068 NP_001007069 NM_001007069 NP_001007070 NM_001007070 NP_001007071 NM_005625 NP_005616
Function Seems to function as an adapter protein. In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA). May also play a role in vesicular trafficking. Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway. {ECO:0000269|PubMed:10230395, ECO:0000269|PubMed:11179419, ECO:0000269|PubMed:11498591}.
Subcellular Location Cell junction, focal adhesion. Cell junction, adherens junction. Cell membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein. Nucleus. Melanosome. Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Note=Mainly membrane-associated. Localized to adherens junctions, focal adhesions and endoplasmic reticulum. Colocalized with actin stress fibers. Also found in the nucleus. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Tissue Specificity Widely expressed. Expressed in fetal kidney, liver, lung and brain. In adult highest expression in heart and placenta.

syntenin-1 CRISPR/Cas9 KO Plasmid (h) - sc-416825 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

syntenin-1 HDR Plasmid (h) - sc-416825-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

syntenin-1 Double Nickase Plasmid (h) - sc-416825-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

syntenin-1 Double Nickase Plasmid (h2) - sc-416825-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

syntenin-1 CRISPR Activation Plasmid (h) - sc-416825-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

syntenin-1 CRISPR Activation Plasmid (h2) - sc-416825-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

syntenin-1 Lentiviral Activation Particles (h) - sc-416825-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

syntenin-1 Lentiviral Activation Particles (h2) - sc-416825-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

syntenin-1 siRNA (h) - sc-42164 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

syntenin-1 shRNA Plasmid (h) - sc-42164-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

syntenin-1 shRNA (h) Lentiviral Particles - sc-42164-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Syntenin 1 RNAi - H00006386-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

Syntenin 1 RNAi - H00006386-R05 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

Syntenin 1 RNAi - H00006386-R04 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

Syntenin 1 RNAi - H00006386-R03 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU111601 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN18989 from Sigma-Aldrich

Category ZFN Kit

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18989 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

SDCBP siRNA (Human) - CRH4311 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Syntenin 1 RNAi - H00006386-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

SDCBP - MBS8224750 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SDCBP (NM_005625.3) - SHH403288 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human SDCBP(NM_001007069.1) - SHR210898 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human SDCBP(NM_001007068.1) - SHR210916 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human SDCBP(NM_001007067.1) - SHR210934 from Creative biogene

Category siRNA
Species Reactivities Human
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