SDCBP

Gene Symbol SDCBP
Entrez Gene 6386
Alt Symbol MDA-9, MDA9, ST1, SYCL, TACIP18
Species Human
Gene Type protein-coding
Description syndecan binding protein (syntenin)
Other Description melanoma differentiation associated protein-9|melanoma differentiation-associated protein 9|pro-TGF-alpha cytoplasmic domain-interacting protein 18|scaffold protein Pbp1|syndecan-binding protein 1|syntenin-1
Swissprots B2R5Q7 B7ZLN2 O43391 O00560 O00173 B4DUH3 Q14CP2
Accessions EAW86812 EAW86813 EAW86814 EAW86815 EAW86816 O00560 AF000652 AAB97144 AF006636 AAC52050 AK128645 AK295198 BAG58197 AK298697 BAG60855 AK300647 BAG62335 AK312274 BAG35204 BC013254 BC113674 AAI13675 BC113676 AAI13677 BC143915 AAI43916 BC143916 AAI43917 BG111210 BG772269 BU160865 HQ258156 ADR82910 U83463 AAB51246 XM_011517571 XP_011515873 NM_001007067 NP_001007068 NM_001007068 NP_001007069 NM_001007069 NP_001007070 NM_001007070 NP_001007071 NM_005625 NP_005616
Function Seems to function as an adapter protein. In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA). May also play a role in vesicular trafficking. Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway. {ECO:0000269|PubMed:10230395, ECO:0000269|PubMed:11179419, ECO:0000269|PubMed:11498591}.
Subcellular Location Cell junction, focal adhesion. Cell junction, adherens junction. Cell membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein. Nucleus. Melanosome. Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Note=Mainly membrane-associated. Localized to adherens junctions, focal adhesions and endoplasmic reticulum. Colocalized with actin stress fibers. Also found in the nucleus. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Tissue Specificity Widely expressed. Expressed in fetal kidney, liver, lung and brain. In adult highest expression in heart and placenta.

syntenin-1 (N-20) - sc-19379 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
syntenin-1 (N-20): sc-19379. Immunofluorescence staining of methanol-fixed MCF7 cells showing membrane localization.

syntenin-1 (H-48) - sc-48742 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
syntenin-1 (H-48): sc-48742. Immunoperoxidase staining of formalin fixed, paraffin-embedded human lymph node tissue showing nuclear and cytoplasmic staining of cells in germinal and non-germinal centers.

syntenin-1 (S-31) - sc-100336 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
syntenin-1 (S-31): sc-100336. Western blot analysis of syntenin-1 expression in Hep G2 whole cell lysate.

Anti-Syntenin antibody - ab19903 from Abcam

Prices $398.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Syntenin antibody (ab19903) at 1 µg/mlLane 1 : HEK 293 lysateLane 2 : Human heart lysate Lane 3 : HEK 293 lysate with Mouse Syntenin peptide (ab20431) at 1 µg/mlLane 4 : Human heart lysate with Mouse Syntenin peptide (ab20431) at 1 µg/mlLysates/proteins at 20 µg per lane.Performed under reducing conditions.

Anti-Syntenin antibody [2H6] - ab128087 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2H6
All lanes : Anti-Syntenin antibody [2H6] (ab128087) at 1/500 dilutionLane 1 : HEK293T cells transfected with pCMV6-ENTRY control cDNALane 2 : HEK293T cells transfected with pCMV6-ENTRY Syntenin cDNALysates/proteins at 5 µg per lane.

Anti-Syntenin antibody [3D9-G9-H4] - ab131190 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3D9-G9-H4
All lanes : Anti-Syntenin antibody [3D9-G9-H4] (ab131190) at 1/1000 dilutionLane 1 : HeLa nuclear extractLane 2 : HeLa cell lysate

Anti-Syntenin antibody [EPR8102] - ab133267 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR8102
Overlay histogram showing SHSY-5Y cells stained with ab133267 (red line). The cells were fixed with 4% paraformaldehyde (10 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab133267, 1/10000 dilution) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-rabbit IgG (H&L) (ab150077) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was rabbit IgG (monoclonal) (0.1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter. This antibody gave a positive signal in SHSY-5Y cells fixed with 80% methanol (5 min)/permeabilized with 0.1% PBS-Tween for 20 min used under the same conditions.

Anti-SDCBP / Syntenin Antibody (aa144-193) - LS-C110959 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SDCBP / Syntenin antibody LS-C110959 Western blot of Fetal Brain lysate.

Anti-SDCBP / Syntenin Antibody (aa215-264) - LS-C110960 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SDCBP / Syntenin antibody LS-C110960 Western blot of Fetal Kidney lysate.

Anti-SDCBP / Syntenin Antibody (aa1-30, AP) - LS-C268861 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SDCBP / Syntenin Antibody (aa1-30, APC) - LS-C268862 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SDCBP / Syntenin Antibody (aa1-30, FITC) - LS-C268864 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SDCBP / Syntenin Antibody (aa1-30, Biotin) - LS-C268863 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SDCBP / Syntenin Antibody (aa1-30, Azide-free, HRP) - LS-C268865 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SDCBP / Syntenin Antibody (aa1-30, PE) - LS-C268867 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SDCBP / Syntenin Antibody (aa101-150) - LS-C40484 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
SDCBP / Syntenin antibody LS-C40484 IHC of formalin-fixed, paraffin-embedded human Kidney. Positive label: Epithelial cells of renal tubule indicated with arrows. Antibody concentration 4-8 ug/ml. Magnification 400X.

Anti-SDCBP / Syntenin Antibody (aa1-30) - LS-C156033 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
SDCBP Antibody western blot of NCI-H460 cell line lysates (35 ug/lane). The SDCBP antibody detected the SDCBP protein (arrow).

Anti-SDCBP / Syntenin Antibody (aa1-30) - LS-C324954 from LifeSpan Bioscience

Prices $435.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SDCBP / Syntenin Antibody (aa1-101, Azide-free) - LS-C328607 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-SDCBP / Syntenin Antibody (aa6-19) IHC-plus™ - LS-B8049 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-Syntenin antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8049 dilution 10 ug/ml.

Anti-SDCBP / Syntenin Antibody - LS-C178274 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot detection of SDCBP in HeLa NE&HeLa cell lysates using SDCBP antibody (1:1000 diluted).

Anti-SDCBP / Syntenin Antibody - LS-C341299 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SDCBP / Syntenin Antibody (Internal, clone EPR8102) IHC-plus™ - LS-B8689 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Monoclonal
Clone EPR8102
Anti-SDCBP / Syntenin antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-SDCBP / Syntenin Antibody - LS-C334009 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human stomach using SDCBP antibody at dilution of 1:200 (x400 lens).

Anti-SDCBP / Syntenin Antibody (clone 2C12) IHC-plus™ - LS-B6146 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2C12
Anti-SDCBP / Syntenin antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6146 concentration 5 ug/ml.
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