Gene Symbol |
SOX6
|
Entrez Gene |
55553
|
Alt Symbol |
HSSOX6, SOXD
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
SRY (sex determining region Y)-box 6
|
Other Description |
SRY-box containing gene 6|transcription factor SOX-6
|
Swissprots |
Q9BXQ3 Q9BXQ4 P35712 Q86VX7 Q9H0I8 Q9BXQ5
|
Accessions |
AAK26243 AAK26244 CCQ43798 EAW68458 EAW68459 EAW68460 P35712 AF309034 AAK26115 AK021785 AK097455 AK310506 AL136780 CAB66714 AL833302 AM392594 CAL37472 AM392730 CAL37608 AM393356 CAL38234 BC029429 BC037866 BC047064 AAH47064 DB080840 DB093816 X65663 CAA46614 NM_001145811 NP_001139283 NM_001145819 NP_001139291 NM_017508 NP_059978 NM_033326 NP_201583
|
Function |
Transcriptional activator. Binds specifically to the DNA sequence 5'-AACAAT-3'. Plays a key role in several developmental processes, including neurogenesis and skeleton formation.
|
Subcellular Location |
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00267, ECO:0000269|PubMed:16442531}.
|
Tissue Specificity |
Expressed in a wide variety of tissues, most abundantly in skeletal muscle. {ECO:0000269|PubMed:11255018}.
|