Gene Symbol | SOX6 |
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Entrez Gene | 55553 |
Alt Symbol | HSSOX6, SOXD |
Species | Human |
Gene Type | protein-coding |
Description | SRY (sex determining region Y)-box 6 |
Other Description | SRY-box containing gene 6|transcription factor SOX-6 |
Swissprots | Q9BXQ3 Q9BXQ4 P35712 Q86VX7 Q9H0I8 Q9BXQ5 |
Accessions | AAK26243 AAK26244 CCQ43798 EAW68458 EAW68459 EAW68460 P35712 AF309034 AAK26115 AK021785 AK097455 AK310506 AL136780 CAB66714 AL833302 AM392594 CAL37472 AM392730 CAL37608 AM393356 CAL38234 BC029429 BC037866 BC047064 AAH47064 DB080840 DB093816 X65663 CAA46614 NM_001145811 NP_001139283 NM_001145819 NP_001139291 NM_017508 NP_059978 NM_033326 NP_201583 |
Function | Transcriptional activator. Binds specifically to the DNA sequence 5'-AACAAT-3'. Plays a key role in several developmental processes, including neurogenesis and skeleton formation. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00267, ECO:0000269|PubMed:16442531}. |
Tissue Specificity | Expressed in a wide variety of tissues, most abundantly in skeletal muscle. {ECO:0000269|PubMed:11255018}. |
Sox-6 CRISPR/Cas9 KO Plasmid (h) - sc-402646 from Santa Cruz Biotechnology
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Sox-6 HDR Plasmid (h) - sc-402646-HDR from Santa Cruz Biotechnology
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Sox-6 Double Nickase Plasmid (h) - sc-402646-NIC from Santa Cruz Biotechnology
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Sox-6 Double Nickase Plasmid (h2) - sc-402646-NIC-2 from Santa Cruz Biotechnology
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Sox-6 CRISPR Activation Plasmid (h) - sc-402646-ACT from Santa Cruz Biotechnology
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Sox-6 CRISPR Activation Plasmid (h2) - sc-402646-ACT-2 from Santa Cruz Biotechnology
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Sox-6 Lentiviral Activation Particles (h) - sc-402646-LAC from Santa Cruz Biotechnology
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Sox-6 Lentiviral Activation Particles (h2) - sc-402646-LAC-2 from Santa Cruz Biotechnology
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Sox-6 siRNA (h) - sc-36531 from Santa Cruz Biotechnology
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Sox-6 shRNA Plasmid (h) - sc-36531-SH from Santa Cruz Biotechnology
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Sox-6 shRNA (h) Lentiviral Particles - sc-36531-V from Santa Cruz Biotechnology
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SOX6 RNAi - H00055553-R02 from Novus Biologicals
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MISSION® esiRNA - EHU157831 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20361 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20361 from Sigma-Aldrich
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SOX6 siRNA (Human) - CRJ0736 from Cohesion Biosciences
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SOX6 RNAi - H00055553-R01 from Novus Biologicals
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SOX6 - MBS8209937 from MyBioSource
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shRNA set against Human SOX6 (NM_033326.3) - SHH415468 from Creative biogene
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Human SOX6 siRNA - orb271237 from Biorbyt
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SOX6 shRNA Plasmid (Human) - CHJ0736 from Cohesion Biosciences
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