| Gene Symbol |
PSMD8
|
| Entrez Gene |
5714
|
| Alt Symbol |
HEL-S-91n, HIP6, HYPF, Nin1p, Rpn12, S14, p31
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
|
| Other Description |
26S proteasome non-ATPase regulatory subunit 8|26S proteasome regulatory subunit RPN12|26S proteasome regulatory subunit S14|26S proteasome regulatory subunit p31|epididymis secretory sperm binding protein Li 91n
|
| Swissprots |
Q6P1L7 P48556 B4DX18
|
| Accessions |
AAC62833 EAW56785 P48556 AK301771 BAG63230 AK304486 BAG65296 AK308809 BC001164 AAH01164 BC065006 AAH65006 BC071826 BI560993 BP369299 BQ684248 BT019688 AAV38494 D38047 BAA07237 EU668354 ACF94507 NM_002812 NP_002803
|
| Function |
Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. Necessary for activation of the CDC28 kinase.
|
| Top Pathways |
Proteasome, Epstein-Barr virus infection
|