Gene Symbol | PSMD8 |
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Entrez Gene | 5714 |
Alt Symbol | HEL-S-91n, HIP6, HYPF, Nin1p, Rpn12, S14, p31 |
Species | Human |
Gene Type | protein-coding |
Description | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 |
Other Description | 26S proteasome non-ATPase regulatory subunit 8|26S proteasome regulatory subunit RPN12|26S proteasome regulatory subunit S14|26S proteasome regulatory subunit p31|epididymis secretory sperm binding protein Li 91n |
Swissprots | Q6P1L7 P48556 B4DX18 |
Accessions | AAC62833 EAW56785 P48556 AK301771 BAG63230 AK304486 BAG65296 AK308809 BC001164 AAH01164 BC065006 AAH65006 BC071826 BI560993 BP369299 BQ684248 BT019688 AAV38494 D38047 BAA07237 EU668354 ACF94507 NM_002812 NP_002803 |
Function | Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. Necessary for activation of the CDC28 kinase. |
Top Pathways | Proteasome, Epstein-Barr virus infection |
PSMD8 CRISPR/Cas9 KO Plasmid (h) - sc-410965 from Santa Cruz Biotechnology
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PSMD8 HDR Plasmid (h) - sc-410965-HDR from Santa Cruz Biotechnology
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PSMD8 Double Nickase Plasmid (h) - sc-410965-NIC from Santa Cruz Biotechnology
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PSMD8 Double Nickase Plasmid (h2) - sc-410965-NIC-2 from Santa Cruz Biotechnology
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PSMD8 CRISPR Activation Plasmid (h) - sc-410965-ACT from Santa Cruz Biotechnology
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PSMD8 CRISPR Activation Plasmid (h2) - sc-410965-ACT-2 from Santa Cruz Biotechnology
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PSMD8 Lentiviral Activation Particles (h) - sc-410965-LAC from Santa Cruz Biotechnology
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PSMD8 Lentiviral Activation Particles (h2) - sc-410965-LAC-2 from Santa Cruz Biotechnology
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PSMD8 siRNA (h) - sc-97286 from Santa Cruz Biotechnology
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PSMD8 shRNA Plasmid (h) - sc-97286-SH from Santa Cruz Biotechnology
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PSMD8 shRNA (h) Lentiviral Particles - sc-97286-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU147871 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17626 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17626 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04314 from Sigma-Aldrich
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PSMD8 siRNA (Human) - CRH3859 from Cohesion Biosciences
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shRNA set against Human PSMD8 (NM_002812.4) - SHH385492 from Creative biogene
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shRNA set against Human PSMD8(NM_002812.4) - SHR148722 from Creative biogene
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PSMD8 shRNA Plasmid (Human) - CHH3859 from Cohesion Biosciences
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PSMD8 miRNA 3'UTR clone - MiUTR1H-08392 from Creative biogene
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