H2AFB1
| Gene Symbol | H2AFB1 |
|---|---|
| Entrez Gene | 474382 |
| Alt Symbol | H2A.Bbd |
| Species | Human |
| Gene Type | protein-coding |
| Description | H2A histone family, member B1 |
| Other Description | H2A Barr body-deficient|histone H2A-Bbd type 1 |
| Swissprots | A0PK90 P0C5Y9 |
| Accessions | P0C5Y9 BC128034 AAI28035 CR542230 CAG47026 NM_001017990 NP_001017990 |
| Function | Atypical histone H2A which can replace conventional H2A in some nucleosomes and is associated with active transcription and mRNA processing. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Nucleosomes containing this histone are less rigid and organize less DNA than canonical nucleosomes in vivo. They are enriched in actively transcribed genes and associate with the elongating form of RNA polymerase. They associate with spliceosome components and are required for mRNA splicing. May participate in spermatogenesis. {ECO:0000269|PubMed:15257289, ECO:0000269|PubMed:16287874, ECO:0000269|PubMed:16957777, ECO:0000269|PubMed:17591702, ECO:0000269|PubMed:17726088, ECO:0000269|PubMed:18329190, ECO:0000269|PubMed:22795134}. |
| Subcellular Location | Nucleus. Chromosome. Note=Associated with the active X chromosome and with autosomes, while it is absent from the inactive X chromosome and excluded from Barr bodies. |
| Tissue Specificity | Present in mature sperm. {ECO:0000269|PubMed:20008104}. |
| Top Pathways | Systemic lupus erythematosus, Alcoholism |
Anti-H2AFB1 Antibody - LS-C183386 from LifeSpan Bioscience
|
||||||||
Acetyl-Histone H2A(K5) Antibody - bs-3781R from Bioss
|
||||||||
H2AFB1 Antibody - N-terminal region (ARP68411_P050) - ARP68411_P050 from Aviva Systems Biology
|
||||||||
Anti -H2AFB1 (Histone H2A-Bbd Type 1, H2A Barr Body-deficient, H2A.Bbd) - 029490 from USBiological Life Science
|
||||||||
H2AFB1 antibody - orb24511 from Biorbyt
|
||||||||
Rabbit Anti-Acetyl-Histone H2A(K5) Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-3781R-A350 from Bioss
|
||||||||
Rabbit Anti-Acetyl-Histone H2A(K5) Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-3781R-A488 from Bioss
|
||||||||
Rabbit Anti-Acetyl-Histone H2A(K5) Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-3781R-A555 from Bioss
|
||||||||
Rabbit Anti-Acetyl-Histone H2A(K5) Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-3781R-A647 from Bioss
|
||||||||
Rabbit Anti-Acetyl-Histone H2A(K5) Polyclonal Antibody, Cy3 Conjugated - bs-3781R-Cy3 from Bioss
|
||||||||
Rabbit Anti-Acetyl-Histone H2A(K5) Polyclonal Antibody, Cy5 Conjugated - bs-3781R-Cy5 from Bioss
|
||||||||
Rabbit Anti-Acetyl-Histone H2A(K5) Polyclonal Antibody, Cy5.5 Conjugated - bs-3781R-Cy5.5 from Bioss
|
||||||||
Rabbit Anti-Acetyl-Histone H2A(K5) Polyclonal Antibody, Cy7 Conjugated - bs-3781R-Cy7 from Bioss
|
||||||||
Rabbit Anti-Acetyl-Histone H2A(K5) Polyclonal Antibody, FITC Conjugated - bs-3781R-FITC from Bioss
|
||||||||
Rabbit Anti-Acetyl-Histone H2A(K5) Polyclonal Antibody, Biotin Conjugated - bs-3781R-Biotin from Bioss
|
||||||||
Rabbit Anti-Acetyl-Histone H2A(K5) Polyclonal Antibody, HRP Conjugated - bs-3781R-HRP from Bioss
|
||||||||
Anti-H2AFB1 (aa 10-59) polyclonal antibody - DPABH-11473 from Creative Diagnostics
|
||||||||
H2AFB1, Polyclonal Antibody - MBS647548 from MyBioSource
|
||||||||
ChIPAb+™ Histone H2A.Bbd - ChIP Validated Antibody and Primer Set - 17-10246 from EMD Millipore
|
||||||||
Anti-Histone H2A.Bbd Antibody - 06-1319 from EMD Millipore
|
||||||||
H2AFB1-Antibody-N-terminal-region-AI15618 - AI15618 from Abgent, a WuXi AppTec company
|
||||||||
H2AFB1 / H2A.Bbd antibody - TA332256 from Acris Antibodies
|
||||||||
H2AFB1 Antibody,Biotin conjugated - CSB-PA010091LD01HU from Cusabio
|
||||||||
H2AFB1 Antibody,FITC conjugated - CSB-PA010091LC01HU from Cusabio
|
||||||||
H2AFB1 Antibody,HRP conjugated - CSB-PA010091LB01HU from Cusabio
|