| Gene Symbol |
MED16
|
| Entrez Gene |
10025
|
| Alt Symbol |
DRIP92, THRAP5, TRAP95
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
mediator complex subunit 16
|
| Other Description |
mediator of RNA polymerase II transcription subunit 16|thyroid hormone receptor-associated protein 5|thyroid hormone receptor-associated protein complex 95 kDa component|thyroid hormone receptor-associated protein, 95-kD subunit|vitamin D3 receptor-interacting protein complex 92 kDa component
|
| Swissprots |
Q9Y652 Q96AD4 Q96I35 Q9Y2X0 Q6PJT2
|
| Accessions |
EAW69586 EAW69587 Q9Y2X0 AF106934 AAD31087 AF121228 AAD30032 AL137732 AU098434 BC004554 AAH04554 BC007853 AAH07853 BC011841 AAH11841 BC017282 AAH17282 BI461485 BQ015734 CB050542 DQ893678 ABM84604 DQ895933 ABM86859 EU392448 ACB88881 EU392449 ACB88882 EU392450 ACB88883 EU392451 ACB88884 EU392452 ACB88885 EU392453 ACB88886 EU392454 ACB88887 EU392455 ACB88888 EU392456 ACB88889 EU392457 ACB88890 EU392458 ACB88891 EU392459 ACB88892 EU392460 ACB88893 EU392461 ACB88894 EU392462 ACB88895 EU392463 ACB88896 EU392464 ACB88897 EU392465 ACB88898 EU392466 ACB88899 EU392467 ACB88900 EU392468 ACB88901 EU392469 ACB88902 EU392470 ACB88903 EU392471 ACB88904 EU392472 ACB88905 EU392473 ACB88906 EU392474 ACB88907 EU392475 ACB88908 EU392476 ACB88909 EU392477 ACB88910 EU392478 ACB88911 EU392479 ACB88912 EU392480 ACB88913 EU392481 ACB88914 EU392482 EU392483 EU392484 EU392485 EU392486 EU392487 EU392488 EU392489 EU392490 EU392491 EU392492 EU392493 EU392494 EU392495 EU392496 EU392497 EU392498 XM_011527604 XP_011525906 XR_936134 NM_005481 NP_005472
|
| Function |
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. {ECO:0000269|PubMed:10198638, ECO:0000269|PubMed:10235266}.
|
| Subcellular Location |
Nucleus {ECO:0000305}.
|