BTC

Gene Symbol BTC
Entrez Gene 685
Alt Symbol -
Species Human
Gene Type protein-coding
Description betacellulin
Other Description probetacellulin
Swissprots P35070 Q96F48
Accessions BAC76611 EAX05712 P35070 AB109441 BAC76609 AM392725 CAL37603 AM392995 CAL37873 AM393303 CAL38181 AM393550 CAL38427 BC011618 AAH11618 S55606 AAB25452 XM_005263190 XP_005263247 XM_011532211 XP_011530513 NM_001729 NP_001720
Function Growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. {ECO:0000269|PubMed:8570211}.
Subcellular Location Betacellulin: Secreted, extracellular space.
Tissue Specificity Synthesized in several tissues and tumor cells. Predominantly expressed in pancreas and small intestine. {ECO:0000269|PubMed:8919026}.
Top Pathways ErbB signaling pathway