Gene Symbol |
BTC
|
Entrez Gene |
685
|
Alt Symbol |
-
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
betacellulin
|
Other Description |
probetacellulin
|
Swissprots |
P35070 Q96F48
|
Accessions |
BAC76611 EAX05712 P35070 AB109441 BAC76609 AM392725 CAL37603 AM392995 CAL37873 AM393303 CAL38181 AM393550 CAL38427 BC011618 AAH11618 S55606 AAB25452 XM_005263190 XP_005263247 XM_011532211 XP_011530513 NM_001729 NP_001720
|
Function |
Growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. {ECO:0000269|PubMed:8570211}.
|
Subcellular Location |
Betacellulin: Secreted, extracellular space.
|
Tissue Specificity |
Synthesized in several tissues and tumor cells. Predominantly expressed in pancreas and small intestine. {ECO:0000269|PubMed:8919026}.
|
Top Pathways |
ErbB signaling pathway
|