Gene Symbol | BTC |
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Entrez Gene | 685 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | betacellulin |
Other Description | probetacellulin |
Swissprots | P35070 Q96F48 |
Accessions | BAC76611 EAX05712 P35070 AB109441 BAC76609 AM392725 CAL37603 AM392995 CAL37873 AM393303 CAL38181 AM393550 CAL38427 BC011618 AAH11618 S55606 AAB25452 XM_005263190 XP_005263247 XM_011532211 XP_011530513 NM_001729 NP_001720 |
Function | Growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. {ECO:0000269|PubMed:8570211}. |
Subcellular Location | Betacellulin: Secreted, extracellular space. |
Tissue Specificity | Synthesized in several tissues and tumor cells. Predominantly expressed in pancreas and small intestine. {ECO:0000269|PubMed:8919026}. |
Top Pathways | ErbB signaling pathway |
BTC CRISPR/Cas9 KO Plasmid (h) - sc-401927 from Santa Cruz Biotechnology
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BTC HDR Plasmid (h) - sc-401927-HDR from Santa Cruz Biotechnology
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BTC Double Nickase Plasmid (h) - sc-401927-NIC from Santa Cruz Biotechnology
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BTC Double Nickase Plasmid (h2) - sc-401927-NIC-2 from Santa Cruz Biotechnology
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BTC CRISPR Activation Plasmid (h) - sc-401927-ACT from Santa Cruz Biotechnology
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BTC CRISPR Activation Plasmid (h2) - sc-401927-ACT-2 from Santa Cruz Biotechnology
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BTC Lentiviral Activation Particles (h) - sc-401927-LAC from Santa Cruz Biotechnology
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BTC Lentiviral Activation Particles (h2) - sc-401927-LAC-2 from Santa Cruz Biotechnology
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BTC siRNA (h) - sc-39414 from Santa Cruz Biotechnology
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BTC shRNA Plasmid (h) - sc-39414-SH from Santa Cruz Biotechnology
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BTC shRNA (h) Lentiviral Particles - sc-39414-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU031331 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN4098 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4098 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03632 from Sigma-Aldrich
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BTC siRNA (Human) - CRH0477 from Cohesion Biosciences
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BTC - MBS8240204 from MyBioSource
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shRNA set against Human BTC (NM_001729.2) - SHH248198 from Creative biogene
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shRNA set against Human BTC(NM_001729.2) - SHG107009 from Creative biogene
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BTC shRNA Plasmid (Human) - CHH0477 from Cohesion Biosciences
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BTC miRNA 3'UTR clone - MiUTR1H-00975 from Creative biogene
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