Gene Symbol | BTC |
---|---|
Entrez Gene | 685 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | betacellulin |
Other Description | probetacellulin |
Swissprots | P35070 Q96F48 |
Accessions | BAC76611 EAX05712 P35070 AB109441 BAC76609 AM392725 CAL37603 AM392995 CAL37873 AM393303 CAL38181 AM393550 CAL38427 BC011618 AAH11618 S55606 AAB25452 XM_005263190 XP_005263247 XM_011532211 XP_011530513 NM_001729 NP_001720 |
Function | Growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. {ECO:0000269|PubMed:8570211}. |
Subcellular Location | Betacellulin: Secreted, extracellular space. |
Tissue Specificity | Synthesized in several tissues and tumor cells. Predominantly expressed in pancreas and small intestine. {ECO:0000269|PubMed:8919026}. |
Top Pathways | ErbB signaling pathway |