Gene Symbol |
DSG3
|
Entrez Gene |
1830
|
Alt Symbol |
CDHF6, PVA
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
desmoglein 3
|
Other Description |
130 kDa pemphigus vulgaris antigen|130-kD pemphigus vulgaris antigen|cadherin family member 6|desmoglein-3|pemphigus vulgaris antigen
|
Swissprots |
P32926 A8K2V2
|
Accessions |
CAJ46922 EAX01258 EAX01259 P32926 AI608626 AK290367 BAF83056 BC063544 BC105997 BX110234 BX507120 BX538327 CAD98098 DA447747 DA458544 M76482 AAA60230 U51696 XM_011525850 XP_011524152 NM_001944 NP_001935
|
Function |
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
|
Subcellular Location |
Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cell junction, desmosome {ECO:0000250}.
|
Tissue Specificity |
Epidermis, tongue, tonsil, esophagus and carcinomas.
|