| Gene Symbol |
CHRNE
|
| Entrez Gene |
1145
|
| Alt Symbol |
ACHRE, CMS1D, CMS1E, CMS2A, FCCMS, SCCMS
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cholinergic receptor, nicotinic, epsilon (muscle)
|
| Other Description |
AchR epsilon subunit|acetylcholine receptor subunit epsilon|acetylcholine receptor, nicotinic, epsilon (muscle)|cholinergic receptor, nicotinic, epsilon polypeptide
|
| Swissprots |
D3DTK6 Q04844
|
| Accessions |
AAD24503 BAB97270 EAW90394 EAW90395 EAW90396 Q04844 AI041890 BC156077 AAI56078 BC157043 AAI57044 X66403 CAA47030 XM_011523631 XP_011521933 NM_000080 NP_000071
|
| Function |
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
|
| Subcellular Location |
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
|
| Top Pathways |
Neuroactive ligand-receptor interaction
|