Gene Symbol | CHRNE |
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Entrez Gene | 1145 |
Alt Symbol | ACHRE, CMS1D, CMS1E, CMS2A, FCCMS, SCCMS |
Species | Human |
Gene Type | protein-coding |
Description | cholinergic receptor, nicotinic, epsilon (muscle) |
Other Description | AchR epsilon subunit|acetylcholine receptor subunit epsilon|acetylcholine receptor, nicotinic, epsilon (muscle)|cholinergic receptor, nicotinic, epsilon polypeptide |
Swissprots | D3DTK6 Q04844 |
Accessions | AAD24503 BAB97270 EAW90394 EAW90395 EAW90396 Q04844 AI041890 BC156077 AAI56078 BC157043 AAI57044 X66403 CAA47030 XM_011523631 XP_011521933 NM_000080 NP_000071 |
Function | After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. |
Subcellular Location | Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
Top Pathways | Neuroactive ligand-receptor interaction |
AChRε siRNA (h) - sc-42542 from Santa Cruz Biotechnology
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AChRε shRNA Plasmid (h) - sc-42542-SH from Santa Cruz Biotechnology
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AChRε shRNA (h) Lentiviral Particles - sc-42542-V from Santa Cruz Biotechnology
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Nicotinic Acetylcholine Receptor epsilon RNAi - H00001145-R01 from Novus Biologicals
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MISSION® esiRNA - EHU139161 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1619 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1619 from Sigma-Aldrich
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CHRNE siRNA (Human) - CRH0822 from Cohesion Biosciences
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CHRNE - MBS8239804 from MyBioSource
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shRNA set against Human CHRNE (NM_000080.3) - SHH263681 from Creative biogene
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Human CHRNE siRNA - orb261324 from Biorbyt
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CHRNE shRNA Plasmid (Human) - CHH0822 from Cohesion Biosciences
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CHRNE miRNA 3'UTR clone - MiUTR3H-00010 from Creative biogene
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