| Gene Symbol |
ABCC4
|
| Entrez Gene |
10257
|
| Alt Symbol |
MOAT-B, MOATB, MRP4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ATP-binding cassette, sub-family C (CFTR/MRP), member 4
|
| Other Description |
MRP/cMOAT-related ABC transporter|bA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4)|canalicular multispecific organic anion transporter (ABC superfamily)|multi-specific organic anion transporter B|multidrug resistance-associated protein 4
|
| Swissprots |
Q8IZN6 Q8IVZ4 Q8NEW8 Q9Y6J2 A9Z1Z7 B7Z3Q7 O15439
|
| Accessions |
CAJ46926 EAX08949 EAX08950 EAX08951 EAX08952 O15439 AB208973 BAD92210 AF071202 AAC27076 AF071203 AAC27077 AF339763 AF541977 AAN17334 AK290317 BAF83006 AK296247 BAH12293 AK298953 BAH12910 AK309460 AY081219 AAL88745 AY133678 AAN08628 AY133679 AAN08629 AY133680 AAN08630 AY207008 AAO37649 BC041560 AAH41560 BM687848 BP382967 BU689822 BX113883 BX647118 CA314196 CN410193 U83660 AAB71757 XM_005254025 XP_005254082 XM_006719914 XP_006719977 XM_011521047 XP_011519349 NM_001105515 NP_001098985 NM_001301829 NP_001288758 NM_001301830 NP_001288759 NM_005845 NP_005836
|
| Function |
May be an organic anion pump relevant to cellular detoxification.
|
| Subcellular Location |
Membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Widely expressed, with particularly high levels in prostate, but is barely detectable in liver.
|
| Top Pathways |
ABC transporters, Bile secretion, cAMP signaling pathway
|
![Western Blot: MRP4 Overexpression Lysate (Adult Normal) [NBP2-11422] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for MRP4.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2022_MRP4%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-11422-img0001.jpg)