ABCC4

Gene Symbol ABCC4
Entrez Gene 10257
Alt Symbol MOAT-B, MOATB, MRP4
Species Human
Gene Type protein-coding
Description ATP-binding cassette, sub-family C (CFTR/MRP), member 4
Other Description MRP/cMOAT-related ABC transporter|bA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4)|canalicular multispecific organic anion transporter (ABC superfamily)|multi-specific organic anion transporter B|multidrug resistance-associated protein 4
Swissprots Q8IZN6 Q8IVZ4 Q8NEW8 Q9Y6J2 A9Z1Z7 B7Z3Q7 O15439
Accessions CAJ46926 EAX08949 EAX08950 EAX08951 EAX08952 O15439 AB208973 BAD92210 AF071202 AAC27076 AF071203 AAC27077 AF339763 AF541977 AAN17334 AK290317 BAF83006 AK296247 BAH12293 AK298953 BAH12910 AK309460 AY081219 AAL88745 AY133678 AAN08628 AY133679 AAN08629 AY133680 AAN08630 AY207008 AAO37649 BC041560 AAH41560 BM687848 BP382967 BU689822 BX113883 BX647118 CA314196 CN410193 U83660 AAB71757 XM_005254025 XP_005254082 XM_006719914 XP_006719977 XM_011521047 XP_011519349 NM_001105515 NP_001098985 NM_001301829 NP_001288758 NM_001301830 NP_001288759 NM_005845 NP_005836
Function May be an organic anion pump relevant to cellular detoxification.
Subcellular Location Membrane; Multi-pass membrane protein.
Tissue Specificity Widely expressed, with particularly high levels in prostate, but is barely detectable in liver.
Top Pathways ABC transporters, Bile secretion, cAMP signaling pathway

MRP4/ABCC4 (D2Q2O) Rabbit mAb - 12705 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D2Q2O
Western blot analysis of extracts from SW620 and U-2 OS cells using ABCC4 (D2Q2O) Rabbit mAb

MRP4/ABCC4 (D1Z3W) Rabbit mAb - 12857 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D1Z3W
Western blot analysis of extracts from membrane fractions of SW620, LNCaP, and HT-29 cells using MRP4/ABCC4 (D1Z3W) Rabbit mAb.

ABCC4 Antibody - 5624 from Cell Signaling Technology

Host Rabbit
Clonality Polyclonal

MRP4 (F-6) - sc-376262 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MRP4 (F-6): sc-376262. Western blot analysis of MRP4 expression in LNCaP whole cell lysate.

MRP4 (H-280) - sc-20768 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
MRP4 (H-280): sc-20768. Western blot analysis of MRP4 expression in CCRF-CEM whole cell lysate.

MRP4 (K-17) - sc-5767 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MRP4 (K-17): sc-5767. Immunoperoxidase staining of formalin fixed, paraffin-embedded human prostate tissue showing membrane staining of glandular cells.

MRP4 (N-18) - sc-5765 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MRP4 (N-18): sc-5765. Western blot analysis of MRP4 expression in A549 whole cell lysate.

MRP4 (M4I-10) - sc-59614 from Santa Cruz Biotechnology

Prices $279.00
Sizes 500 µl supernatant
Host Rat
Clonality Monoclonal

Anti-MRP4 antibody - ab56675 from Abcam

Prices $390.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-MRP4 antibody - ab77184 from Abcam

Prices $378.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-MRP4 antibody (ab77184) at 0.5 µg/ml + rat renal cortex membranes at 20 µg

Anti-MRP4 antibody - ab180712 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human esophagus tissue labelling MRP4 with ab180712 at 1/200. Magnification: 200x.

Anti-MRP4 antibody - ab32550 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MRP4 antibody (ab32550) at 1 µg/mlLane 1 : Prostate (Human) Tissue Lysate Lane 2 : Kidney (Human) Tissue Lysate - adult normal tissue (ab30203)Lysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-MRP4 antibody - ab112541 from Abcam

Prices $376.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-MRP4 antibody (ab112541) at 0.3 µg/ml + Human Prostate lysate (in RIPA buffer) at 35 µgdeveloped using the ECL technique

Anti-MRP4 antibody [2D2A9] - ab175364 from Abcam

Prices $384.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2D2A9
All lanes : Anti-MRP4 antibody [2D2A9] (ab175364) at 1/500 dilutionLane 1 : non transfected HEK293 cell lysate.Lane 2 : MRP4 (aa 631-692)-hIgGFc transfected HEK293 cell lysate.

Anti-MRP4 antibody [6A7H3] - ab175367 from Abcam

Prices $384.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 6A7H3
Anti-MRP4 antibody [6A7H3] (ab175367) at 1/500 dilution + Human MRP4 recombinant protein at 1 µg

Anti-MRP4 antibody [M4I-10] - ab15602 from Abcam

Prices $385.00
Sizes 500 µl
Host Rat
Clonality Monoclonal
Clone M4I-10
HC image of MRP4 staining in Human lung adenocarcinoma formalin fixed paraffin embedded tissue section, performed on a Leica Bond™ system using the standard protocol B. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab15602, 10µg/ml, for 15 mins at room temperature. A Goat anti-Rat biotinylated secondary antibody was used to detect the primary, and visualized using an HRP conjugated ABC system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-MRP4 antibody [M4I-80] - ab15598 from Abcam

Host Rat
Clonality Monoclonal
Clone M4I-80
IHC image of ab15598 staining in human normal kidney formalin fixed paraffin embedded tissue section, performed on a Leica BondTM system using the standard protocol B. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab15598, 5µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-MRP4 antibody - C-terminal - ab82296 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-MRP4 antibody - C-terminal (ab82296) at 1/50 dilution + CEM cell line lysate at 35 µg

Anti-ABCC4 / MRP4 Antibody (aa1-110, Azide-free) - LS-C122145 from LifeSpan Bioscience

Prices $725.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-ABCC4 / MRP4 Antibody (clone M4I-80) - LS-C146610 from LifeSpan Bioscience

Prices $325.00
Sizes 1 ml
Host Rat
Clonality Monoclonal
Clone M4I-80

Anti-ABCC4 / MRP4 Antibody (aa70-82) - LS-C186435 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-ABCC4 / MRP4 Antibody (aa1117-1145) - LS-C100637 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of anti-ABCC4 Antibody in CEM cell line lysates (35 ug/lane). ABCC4 (arrow) was detected using the purified antibody.

Anti-ABCC4 / MRP4 Antibody (aa1231-1280) - LS-C145853 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ABCC4 / MRP4 antibody LS-C145853 Western blot of 721_B Cell lysate. Antibody concentration 1 ug/ml.

Anti-ABCC4 / MRP4 Antibody (clone M4I-10) - LS-C202634 from LifeSpan Bioscience

Prices $325.00
Sizes 1 ml
Host Rat
Clonality Monoclonal
Clone M4I-10

Anti-ABCC4 / MRP4 Antibody - LS-C193103 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot.
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