Gene Symbol | TDRD5 |
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Entrez Gene | 163589 |
Alt Symbol | TUDOR3 |
Species | Human |
Gene Type | protein-coding |
Description | tudor domain containing 5 |
Other Description | tudor domain-containing protein 5 |
Swissprots | A1L4G5 Q6ZSK2 B7ZLV0 Q8NAT2 Q5VTV0 Q5EBN4 |
Accessions | EAW91051 EAW91052 EAW91053 EAW91054 Q8NAT2 AK092142 BAC03815 AK126889 AK127370 BAC86946 BC043368 AAH43368 BC065707 BC089387 AAH89387 BC130532 AAI30533 BC144058 AAI44059 BG771449 DA418635 DB073297 XM_005244934 XP_005244991 XM_005244935 XP_005244992 NM_001199085 NP_001186014 NM_001199089 NP_001186018 NM_001199091 NP_001186020 NM_001199092 NP_001186021 NM_173533 NP_775804 |
Function | Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body (CB) assembly (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Note=Localizes to chromatoid body (CB) and pi-body (also called intermitochondrial cementin), 2 cytoplasmic ribonucleoprotein granules involved in RNA processing for spermatogenesis. {ECO:0000250}. |
TDRD5 (N-15) - sc-244280 from Santa Cruz Biotechnology
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Anti-TDRD5 antibody - ab118424 from Abcam
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Anti-TDRD5 antibody - ab121439 from Abcam
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TDRD5 Antibody - NBP1-81971 from Novus Biologicals
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TDRD5 Antibody - NBP1-81972 from Novus Biologicals
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Anti-TDRD5 antibody produced in rabbit - HPA014563 from Sigma-Aldrich
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Anti-TDRD5 antibody produced in rabbit - HPA029418 from Sigma-Aldrich
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TDRD5 antibody - 25239-1-AP from Acris Antibodies
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TDRD5 antibody - 25239-1-AP from Proteintech Group
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Anti-TDRD5 (aa 700-800) polyclonal antibody - DPABH-08647 from Creative Diagnostics
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Rabbit Anti-Human TDRD5 Polyclonal antibody - DPABH-17821 from Creative Diagnostics
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anti-TDRD5 antibody - A008579 from Biobool
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Anti-TDRD5 Antibody - LS-C660956 from LifeSpan Bioscience
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TDRD5, Polyclonal Antibody - MBS7604812 from MyBioSource
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TDRD5 antibody - orb395666 from Biorbyt
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