FASN

Gene Symbol FASN
Entrez Gene 2194
Alt Symbol FAS, OA-519, SDR27X1
Species Human
Gene Type protein-coding
Description fatty acid synthase
Other Description short chain dehydrogenase/reductase family 27X, member 1
Swissprots Q13479 Q969R1 P49327 Q4LE83 Q96C68 Q6P4U5 Q6SS02 Q16702 Q96IT0
Accessions AAC50536 EAW89745 P49327 AB209988 BAE06070 AY451392 AAS09886 BC007267 AAH07267 BC007305 BC007909 AAH07909 BC014631 AAH14631 BC014634 AAH14634 BC021544 BC063242 AAH63242 S80437 AAB35516 U26644 AAC50259 U29344 AAA73576 XM_011523538 XP_011521840 NM_004104 NP_004095
Function Fatty acid synthetase catalyzes the formation of long- chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:17081065}. Melanosome {ECO:0000269|PubMed:17081065}. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Tissue Specificity Ubiquitous. Prominent expression in brain, lung, and liver. {ECO:0000269|PubMed:7567999, ECO:0000269|PubMed:7595075}.
Top Pathways Insulin signaling pathway, AMPK signaling pathway, Fatty acid biosynthesis, Fatty acid metabolism

SignalSilence ® Fatty Acid Synthase siRNA II - 12613 from Cell Signaling Technology

Category siRNA
Prices $256.00
Sizes 300 µl (3 nmol)
Species Reactivities Human
Western blot analysis of extracts from HeLa cells, transfected with 100 nM SignalSilence ® Control siRNA (Unconjugated) #6568 (-), SignalSilence ® Fatty Acid Synthase siRNA I #12588 (+), or SignalSilence ® Fatty Acid Synthase siRNA II (+), using Fatty Acid Synthase (C20G5) Rabbit mAb #3180 (upper) or β-Actin (D6A8) Rabbit mAb #8457 (lower). The Fatty Acid Synthase (C20G5) Rabbit mAb confirms silencing of fatty acid synthase expression, while the β-Actin (D6A8) Rabbit mAb is used as a loading control.

SignalSilence ® Fatty Acid Synthase siRNA I - 12588 from Cell Signaling Technology

Category siRNA
Western blot analysis of extracts from HeLa cells, transfected with 100 nM SignalSilence ® Control siRNA (Unconjugated) #6568 (-), SignalSilence ® Fatty Acid Synthase siRNA I (+), or SignalSilence ® Fatty Acid Synthase siRNA II #12613 (+), using Fatty Acid Synthase (C20G5) Rabbit mAb #3180 (upper) or β-Actin (D6A8) Rabbit mAb #8457 (lower). The Fatty Acid Synthase (C20G5) Rabbit mAb confirms silencing of fatty acid synthase expression, while the β-Actin (D6A8) Rabbit mAb is used as a loading control.

Fatty Acid Synthase CRISPR/Cas9 KO Plasmid (h) - sc-400440 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Fatty Acid Synthase HDR Plasmid (h) - sc-400440-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Fatty Acid Synthase Double Nickase Plasmid (h) - sc-400440-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Fatty Acid Synthase Double Nickase Plasmid (h2) - sc-400440-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Fatty Acid Synthase CRISPR Activation Plasmid (h) - sc-400440-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Fatty Acid Synthase CRISPR Activation Plasmid (h2) - sc-400440-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Fatty Acid Synthase Lentiviral Activation Particles (h) - sc-400440-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Fatty Acid Synthase Lentiviral Activation Particles (h2) - sc-400440-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Fatty Acid Synthase siRNA (h) - sc-43758 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Fatty Acid Synthase shRNA Plasmid (h) - sc-43758-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Fatty Acid Synthase shRNA (h) Lentiviral Particles - sc-43758-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Fatty Acid Synthase/FASN RNAi - H00002194-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU130711 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2194 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2194 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

FASN siRNA (Human) - CRH1530 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FASN - MBS8238586 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human FASN (NM_004104.4) - SHH292505 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human FASN(NM_004104.4) - SHH049529 from Creative biogene

Category siRNA
Species Reactivities Human

FASN shRNA Plasmid (Human) - CHH1530 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

FASN miRNA 3'UTR clone - MiUTR1H-03519 from Creative biogene

Species Reactivities Human
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