| Gene Symbol |
KRTAP4-1
|
| Entrez Gene |
85285
|
| Alt Symbol |
KAP4.1, KAP4.10, KRTAP4-10, KRTAP4.10
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
keratin associated protein 4-1
|
| Other Description |
keratin associated protein 4-10|keratin-associated protein 4-1|keratin-associated protein 4.1|ultrahigh sulfur keratin-associated protein 4.10
|
| Swissprots |
Q9BYQ7 Q3SYF2 A8MWS7
|
| Accessions |
EAW60715 Q9BYQ7 AJ406942 CAC27581 BC065372 BC103845 AAI03846 BC103846 AAI03847 NM_033060 NP_149049
|
| Function |
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins.
|
| Tissue Specificity |
Expressed in the hair follicles. {ECO:0000269|PubMed:15955084}.
|