Gene Symbol | KRTAP4-1 |
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Entrez Gene | 85285 |
Alt Symbol | KAP4.1, KAP4.10, KRTAP4-10, KRTAP4.10 |
Species | Human |
Gene Type | protein-coding |
Description | keratin associated protein 4-1 |
Other Description | keratin associated protein 4-10|keratin-associated protein 4-1|keratin-associated protein 4.1|ultrahigh sulfur keratin-associated protein 4.10 |
Swissprots | Q9BYQ7 Q3SYF2 A8MWS7 |
Accessions | EAW60715 Q9BYQ7 AJ406942 CAC27581 BC065372 BC103845 AAI03846 BC103846 AAI03847 NM_033060 NP_149049 |
Function | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins. |
Tissue Specificity | Expressed in the hair follicles. {ECO:0000269|PubMed:15955084}. |
KRTAP4-1 CRISPR/Cas9 KO Plasmid (h) - sc-417051 from Santa Cruz Biotechnology
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KRTAP4-1 HDR Plasmid (h) - sc-417051-HDR from Santa Cruz Biotechnology
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KRTAP4-1 Double Nickase Plasmid (h) - sc-417051-NIC from Santa Cruz Biotechnology
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KRTAP4-1 Double Nickase Plasmid (h2) - sc-417051-NIC-2 from Santa Cruz Biotechnology
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KRTAP4-1 CRISPR Activation Plasmid (h) - sc-417051-ACT from Santa Cruz Biotechnology
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KRTAP4-1 CRISPR Activation Plasmid (h2) - sc-417051-ACT-2 from Santa Cruz Biotechnology
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KRTAP4-1 Lentiviral Activation Particles (h) - sc-417051-LAC from Santa Cruz Biotechnology
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KRTAP4-1 Lentiviral Activation Particles (h2) - sc-417051-LAC-2 from Santa Cruz Biotechnology
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KRTAP4-1 siRNA (h) - sc-93761 from Santa Cruz Biotechnology
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KRTAP4-1 shRNA Plasmid (h) - sc-93761-SH from Santa Cruz Biotechnology
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KRTAP4-1 shRNA (h) Lentiviral Particles - sc-93761-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN11469 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11469 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03614 from Sigma-Aldrich
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KRTAP4-1 siRNA (Human) - CRJ3766 from Cohesion Biosciences
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shRNA set against Human KRTAP4-10(NM_033060.2) - SHH139529 from Creative biogene
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Human KRTAP4-1 siRNA - orb274267 from Biorbyt
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KRTAP4-1 shRNA Plasmid (Human) - CHJ3766 from Cohesion Biosciences
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KRTAP4-1 miRNA 3'UTR clone - MiUTR1H-05516 from Creative biogene
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