| Gene Symbol |
AFG3L2
|
| Entrez Gene |
10939
|
| Alt Symbol |
SCA28, SPAX5
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
AFG3-like AAA ATPase 2
|
| Other Description |
AFG3 ATPase family gene 3-like 2|AFG3 ATPase family member 3-like 2|AFG3-like protein 2|ATPase family gene 3, yeast|paraplegin-like protein
|
| Swissprots |
Q6P1L0 Q9Y4W6
|
| Accessions |
EAX01551 EAX01552 Q9Y4W6 AK129504 BC024282 AAH24282 BC065016 AAH65016 BU786821 BX091241 DN993083 Y18314 CAB48398 XM_011525601 XP_011523903 NM_006796 NP_006787
|
| Function |
ATP-dependent protease which is essential for axonal development. {ECO:0000250}.
|
| Subcellular Location |
Mitochondrion membrane {ECO:0000269|PubMed:10395799}; Multi-pass membrane protein {ECO:0000269|PubMed:10395799}.
|
| Tissue Specificity |
Ubiquitous. Highly expressed in the cerebellar Purkinje cells. {ECO:0000269|PubMed:20208537}.
|