ENTPD5

Gene Symbol	ENTPD5
Entrez Gene	957
Alt Symbol	CD39L4, NTPDase-5, PCPH
Species	Human
Gene Type	protein-coding
Description	ectonucleoside triphosphate diphosphohydrolase 5
Other Description	CD39 antigen-like 4|CD39-like 4|ER-UDPase|GDPase ENTPD5|NTPDase 5|Pcph proto-oncogene protein|UDPase ENTPD5|guanosine-diphosphatase ENTPD5|nucleoside diphosphatase|proto-oncogene CPH|uridine-diphosphatase ENTPD5
Swissprots	Q96RX0 O75356 A1L4C5
Accessions	EAW81149 EAW81150 EAW81151 EAW81152 EAW81153 EAW81154 EAW81155 EAW81156 O75356 AF039918 AAC39885 AF136572 AAK82950 AK025209 AY430094 AAR06666 BC020966 BC107878 BC130485 AAI30486 BC130487 AAI30488 DB017355 HQ258244 ADR82998 HQ258615 ADR83367 XM_005268221 XP_005268278 XM_005268222 XP_005268279 XM_005268224 XP_005268281 XM_006720324 XP_006720387 XM_006720325 XP_006720388 XM_006720326 XP_006720389 XM_011537385 XP_011535687 XM_011537386 XP_011535688 NM_001249 NP_001240
Function	Uridine diphosphatase (UDPase) that promotes protein N- glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. The nucleotide hydrolyzing preference is GDP > IDP > UDP, but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling. {ECO:0000269|PubMed:10400613}.
Subcellular Location	Endoplasmic reticulum {ECO:0000250}. Secreted {ECO:0000269|PubMed:10400613}.
Tissue Specificity	Expressed in adult liver, kidney, prostate, testis and colon. Much weaker expression in other tissues. {ECO:0000269|PubMed:9676430}.
Top Pathways	Purine metabolism, Pyrimidine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CD39L4 (C-6) - sc-377172 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

CD39L4 (F-4) - sc-377256 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

CD39L4 (H-79) - sc-134630 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

CD39L4 (K-15) - sc-162654 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-ENTPD5 antibody - ab126151 from Abcam Prices $376.00 Sizes 50 µl Host Rabbit Clonality Polyclonal

Anti-ENTPD5 antibody - ab189406 from Abcam Prices $376.00 Sizes 50 µl Host Rabbit Clonality Polyclonal

Anti-ENTPD5 antibody - ab96067 from Abcam Prices $376.00 Sizes 50 µl Host Rabbit Clonality Polyclonal

Anti-ENTPD5 antibody - ab118660 from Abcam Prices $376.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-ENTPD5 antibody [EPR3783] - ab92542 from Abcam Prices $379.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR3783

Anti-ENTPD5 antibody [EPR3784] - ab108603 from Abcam Prices $381.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR3784

Anti-ENTPD5 / CD39L4 Antibody (aa21-428, clone 12K84) - LS-C182840 from LifeSpan Bioscience Prices $485.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 12K84

Anti-ENTPD5 / CD39L4 Antibody (aa319-401, clone 10C36, Azide-free) - LS-C183584 from LifeSpan Bioscience Host Mouse Clonality Monoclonal Clone 10C36

Anti-ENTPD5 / CD39L4 Antibody (aa333-363, APC) - LS-C234973 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ENTPD5 / CD39L4 Antibody (aa333-363, AP) - LS-C234974 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ENTPD5 / CD39L4 Antibody (aa333-363, Biotin) - LS-C234975 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ENTPD5 / CD39L4 Antibody (aa333-363, FITC) - LS-C234976 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ENTPD5 / CD39L4 Antibody (aa85-134) - LS-C145881 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-ENTPD5 / CD39L4 Antibody (aa333-363, PE) - LS-C234981 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ENTPD5 / CD39L4 Antibody (Internal, clone EPR3783) - LS-C105643 from LifeSpan Bioscience Prices $475.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR3783

Anti-ENTPD5 / CD39L4 Antibody - LS-C155257 from LifeSpan Bioscience Prices $335.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-ENTPD5 / CD39L4 Antibody (Internal, clone EPR3784) - LS-C137898 from LifeSpan Bioscience Prices $480.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR3784

Anti-ENTPD5 / CD39L4 Antibody (aa333-363, Azide-free, HRP) - LS-C249916 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ENTPD5 / CD39L4 Antibody (aa333-363) - LS-C159535 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-ENTPD5 / CD39L4 Antibody (aa333-363) - LS-C329504 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ENTPD5 / CD39L4 Antibody (clone 4A5) - LS-C196860 from LifeSpan Bioscience Prices $355.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 4A5

Search more