MMACHC

Gene Symbol MMACHC
Entrez Gene 25974
Alt Symbol cblC
Species Human
Gene Type protein-coding
Description methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
Other Description methylmalonic aciduria and homocystinuria type C protein
Swissprots Q9BRQ7 Q5T157 Q9Y4U1
Accessions EAX06983 Q9Y4U1 AK098537 AL080062 CAB45693 BC006122 AAH06122 BM980565 BU632364 BU839693 JF432592 ADZ15809 XM_005270724 XP_005270781 XM_011541204 XP_011539506 NM_015506 NP_056321
Function May be involved in the binding and intracellular trafficking of cobalamin (vitamin B12).
Subcellular Location Cytoplasm {ECO:0000269|PubMed:23270877}.
Tissue Specificity Widely expressed. Expressed at higher level in fetal liver. Also expressed in spleen, lymph node, thymus and bone marrow. Weakly or not expressed in peripheral blood leukocytes. {ECO:0000269|PubMed:16311595}.
Top Pathways Vitamin digestion and absorption

MMACHC (A-13) - sc-161860 from Santa Cruz Biotechnology

Host Goat
Clonality Polyclonal

MMACHC (D-12) - sc-161861 from Santa Cruz Biotechnology

Host Goat
Clonality Polyclonal

MMACHC (FL-282) - sc-368223 from Santa Cruz Biotechnology

Host Rabbit
Clonality Polyclonal

MMACHC (N-13) - sc-161862 from Santa Cruz Biotechnology

Host Goat
Clonality Polyclonal

Anti-MMACHC antibody - ab68678 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-MMACHC antibody (ab68678) at 1/500 dilutionLane 1 : MMACHC transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-MMACHC antibody [2A6] - ab127984 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2A6
All lanes : Anti-MMACHC antibody [2A6] (ab127984) at 1/2000 dilutionLane 1 : HEK293T cells transfected with pCMV6-ENTRY control cDNA Lane 2 : HEK293T cells transfected with pCMV6-ENTRY MMACHC cDNA Lysates/proteins at 5 µg per lane.

Anti-MMACHC antibody [EPR11268] - ab177956 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11268
Western blot analysis on immunoprecipitation pellet from HepG2 cell lysate using ab177956.

Anti-MMACHC antibody - C-terminal - ab156236 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-MMACHC antibody - C-terminal (ab156236) at 1/100 dilution + K562 cell line lysates at 35 µg

Anti-MMACHC Antibody (clone 1A4) - LS-C337789 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1A4
IHC of paraffin-embedded Human prostate tissue using anti-MMACHC mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).

Anti-MMACHC Antibody (clone 4E12) - LS-C174084 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4E12
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MMACHC (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MMACHC.

Anti-MMACHC Antibody (clone 1B7) - LS-C174052 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1B7
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MMACHC (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MMACHC.

Anti-MMACHC Antibody (clone 6H5) - LS-C174064 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 6H5
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MMACHC (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MMACHC.

Anti-MMACHC Antibody (clone 6B5) - LS-C174134 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 6B5
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MMACHC (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MMACHC.

Anti-MMACHC Antibody (clone 1E7) - LS-C337785 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1E7
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MMACHC (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MMACHC.

Anti-MMACHC Antibody (aa1-218) - LS-C185841 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded C2C12 xenograft using MMACHC antibody at 1:500 dilution.

Anti-MMACHC Antibody (aa190-239) - LS-C145664 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MMACHC antibody LS-C145664 Western blot of U937 Cell lysate. Antibody concentration 1 ug/ml.

Anti-MMACHC Antibody (aa239-267) - LS-C157889 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
MMACHC Antibody western blot of K562 cell line lysates (35 ug/lane). The MMACHC antibody detected the MMACHC protein (arrow).

Anti-MMACHC Antibody (aa239-267, AP) - LS-C263245 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MMACHC Antibody (aa239-267, APC) - LS-C263247 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MMACHC Antibody (aa239-267, Biotin) - LS-C263248 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MMACHC Antibody (aa239-267, FITC) - LS-C263249 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MMACHC Antibody (aa239-267, Azide-free, HRP) - LS-C263250 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MMACHC Antibody (aa239-267, PE) - LS-C263251 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MMACHC Antibody (clone 4E9) - LS-C173770 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4E9
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MMACHC (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MMACHC.

Anti-MMACHC Antibody - LS-C309022 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
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