| Gene Symbol |
HAUS8
|
| Entrez Gene |
93323
|
| Alt Symbol |
DGT4, HICE1, NY-SAR-48
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
HAUS augmin-like complex, subunit 8
|
| Other Description |
HAUS augmin-like complex subunit 8|HEC1/NDC80 interacting, centrosome associated 1|HEC1/NDC80-interacting centrosome-associated protein 1|Hec1-interacting and centrosome-associated 1|sarcoma antigen NY-SAR-48
|
| Swissprots |
Q9BT25 Q86WF0 C9JBZ4 B4DJA7 Q49AC4 Q96FX3
|
| Accessions |
EAW84570 EAW84571 Q9BT25 AK295994 BAG58769 AY211919 AAO65172 BC004398 AAH04398 BC010176 AAH10176 BC040564 BI829542 BM563712 BX111116 XM_005260154 XP_005260211 XM_011528438 XP_011526740 NM_001011699 NP_001011699 NM_033417 NP_219485
|
| Function |
Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. {ECO:0000269|PubMed:18362163, ECO:0000269|PubMed:19369198, ECO:0000269|PubMed:19427217}.
|
| Subcellular Location |
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=During interphase, primarily cytoplasmic and associates with centrosomes and with the mitotic spindles, preferentially at the spindle pole vicinity. During anaphase and telophase, additionally associates with the spindle midzone and midbody, respectively.
|
![Western Blot: NYS48 Overexpression Lysate (Adult Normal) [NBP2-05878] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for NYS48.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6304_NYS48%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-05878-img0001.jpg)