Gene Symbol | ST3GAL1 |
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Entrez Gene | 6482 |
Alt Symbol | Gal-NAc6S, SIAT4A, SIATFL, ST3GalA, ST3GalA.1, ST3GalIA, ST3GalIA,1, ST3O |
Species | Human |
Gene Type | protein-coding |
Description | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
Other Description | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1|Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase|SIAT4-A|ST3GalI|alpha 2,3-ST 1|beta-galactoside alpha-2,3-sialyltransferase 1|sialyltransferase 4A (beta-galactosidase alpha-2,3-sialytransferase)|sialyltransferase 4A (beta-galactoside alpha-2,3-sialyltransferase)|sialyltransferase 4A (beta-galactoside alpha-2,3-sialytransferase) |
Swissprots | O60677 Q9UN51 Q11201 |
Accessions | CAS91688 EAW92172 EAW92173 EAW92174 Q11201 AF059321 AAC17874 AK093867 AK311319 AL709325 AL833743 BC018357 AAH18357 BC048803 BC063665 BX537506 BX648001 CN359425 DQ891156 ABM82082 DQ894335 ABM85261 L13972 AAC37574 L29555 AAA36612 XM_005251023 XP_005251080 XM_005251024 XP_005251081 XM_005251025 XP_005251082 XM_006716617 XP_006716680 XM_011517225 XP_011515527 XM_011517226 XP_011515528 NM_003033 NP_003024 NM_173344 NP_775479 |
Function | It may be responsible for the synthesis of the sequence NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- found on sugar chains O- linked to Thr or Ser and also as a terminal sequence on certain gangliosides. SIAT4A and SIAT4B sialylate the same acceptor substrates but exhibit different Km values. |
Subcellular Location | Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted. Note=Membrane- bound form in trans cisternae of Golgi. Secreted into the body fluid. |
Tissue Specificity | Expressed in several tissues. Highest expression in lung, liver, skeletal muscle, kidney, pancreas, spleen and placenta. |
Top Pathways | Mucin type O-Glycan biosynthesis, Glycosaminoglycan biosynthesis - keratan sulfate, Glycosphingolipid biosynthesis - globo series, Glycosphingolipid biosynthesis - ganglio series |
Anti-SIAT4A antibody - ab172134 from Abcam
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Anti-ST3GAL1 Antibody (aa1-195) - LS-C185763 from LifeSpan Bioscience
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Anti-ST3GAL1 Antibody (aa254-303) - LS-C80720 from LifeSpan Bioscience
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ST3 beta-Gal alpha-2,3-Sialyltransferase 1/ST3GAL1/SIAT4A Antibody - AF6905 from Novus Biologicals
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ST3 beta-Gal alpha-2,3-Sialyltransferase 1/ST3GAL1/SIAT4A Antibody - NBP1-31449 from Novus Biologicals
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ST3 beta-Gal alpha-2,3-Sialyltransferase 1/ST3GAL1/SIAT4A Antibody - NBP1-87045 from Novus Biologicals
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ST3 beta-Gal alpha-2,3-Sialyltransferase 1/ST3GAL1/SIAT4A Antibody - NBP1-62540 from Novus Biologicals
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ST3 beta-Gal alpha-2,3-Sialyltransferase 1/ST3GAL1/SIAT4A Antibody - H00006482-D01P from Novus Biologicals
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ST3 beta-Gal alpha-2,3-Sialyltransferase 1/ST3GAL1/SIAT4A Antibody - H00006482-B01P from Novus Biologicals
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ST3 beta-Gal alpha-2,3-Sialyltransferase 1/ST3GAL1/SIAT4A Antibody - H00006482-A01 from Novus Biologicals
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Anti-ST3GAL1 antibody produced in rabbit - HPA040466 from Sigma-Aldrich
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Anti-ST3GAL1 antibody produced in rabbit - AV45410 from Sigma-Aldrich
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Anti-ST3GAL1 antibody produced in rabbit - SAB1411274 from Sigma-Aldrich
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Anti-ST3GAL1 antibody produced in mouse - SAB1406438 from Sigma-Aldrich
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ST3GAL1 antibody - C-terminal region (ARP45410_P050) - ARP45410_P050 from Aviva Systems Biology
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Human ST3 beta -Gal alpha -2,3-Sialyltransferase 1/ST3GAL1 Antibody - AF6905 from R&D Systems
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Human ST3GAL1 Affinity Purified Polyclonal Ab, Sheep IgG - AF6905-SP from R&D Systems
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ST3GAL1 antibody - orb69753 from Biorbyt
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ST3GAL1 antibody - 70R-7382 from Fitzgerald
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ST3GAL1 antibody (OAGA00459) - OAGA00459 from Aviva Systems Biology
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SIAT4A antibody - 70R-12959 from Fitzgerald
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ST3GAL1 / SIAT4 antibody - H00006482-A01 from Acris Antibodies
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ST3GAL1 / SIAT4 antibody - H00006482-B01P from Acris Antibodies
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ST3GAL1 / SIAT4 antibody - H00006482-D01P from Acris Antibodies
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Rabbit Anti-Human SIAT4A - 107-10584 from RayBiotech
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