| Gene Symbol |
SLC7A11
|
| Entrez Gene |
23657
|
| Alt Symbol |
CCBR1, xCT
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
|
| Other Description |
amino acid transport system xc-|calcium channel blocker resistance protein CCBR1|cystine/glutamate transporter|solute carrier family 7 member 11|solute carrier family 7, (cationic amino acid transporter, y+ system) member 11
|
| Swissprots |
A8K2U4 Q9UPY5
|
| Accessions |
AAY41053 BAA94999 EAX05135 Q9UPY5 AB026891 BAA82628 AB040875 BAB40574 AF200708 AAG35592 AF252872 AAK49111 AJ277882 CAC81905 AK290359 BAF83048 AK314855 BAG37372 BC012087 AAH12087 BC041925 CD639041 HG497300 HG497301 JF432710 ADZ15927 XM_011531800 XP_011530102 XM_011531801 XP_011530103 XM_011531802 XP_011530104 XM_011531803 XP_011530105 XM_011531804 XP_011530106 XM_011531805 XP_011530107 NM_014331 NP_055146
|
| Function |
Sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine and glutamate. {ECO:0000269|PubMed:15151999}.
|
| Subcellular Location |
Membrane {ECO:0000269|PubMed:15151999}; Multi-pass membrane protein {ECO:0000269|PubMed:15151999}.
|
![Western Blot: xCT Overexpression Lysate (Adult Normal) [NBL1-16185] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for xCT.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/172_xCT%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-16185-img0002.jpg)