Gene Symbol | SLC7A11 |
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Entrez Gene | 23657 |
Alt Symbol | CCBR1, xCT |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
Other Description | amino acid transport system xc-|calcium channel blocker resistance protein CCBR1|cystine/glutamate transporter|solute carrier family 7 member 11|solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 |
Swissprots | A8K2U4 Q9UPY5 |
Accessions | AAY41053 BAA94999 EAX05135 Q9UPY5 AB026891 BAA82628 AB040875 BAB40574 AF200708 AAG35592 AF252872 AAK49111 AJ277882 CAC81905 AK290359 BAF83048 AK314855 BAG37372 BC012087 AAH12087 BC041925 CD639041 HG497300 HG497301 JF432710 ADZ15927 XM_011531800 XP_011530102 XM_011531801 XP_011530103 XM_011531802 XP_011530104 XM_011531803 XP_011530105 XM_011531804 XP_011530106 XM_011531805 XP_011530107 NM_014331 NP_055146 |
Function | Sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine and glutamate. {ECO:0000269|PubMed:15151999}. |
Subcellular Location | Membrane {ECO:0000269|PubMed:15151999}; Multi-pass membrane protein {ECO:0000269|PubMed:15151999}. |
xCT CRISPR/Cas9 KO Plasmid (h) - sc-401920 from Santa Cruz Biotechnology
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xCT HDR Plasmid (h) - sc-401920-HDR from Santa Cruz Biotechnology
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xCT Double Nickase Plasmid (h) - sc-401920-NIC from Santa Cruz Biotechnology
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xCT Double Nickase Plasmid (h2) - sc-401920-NIC-2 from Santa Cruz Biotechnology
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xCT CRISPR Activation Plasmid (h) - sc-401920-ACT from Santa Cruz Biotechnology
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xCT CRISPR Activation Plasmid (h2) - sc-401920-ACT-2 from Santa Cruz Biotechnology
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xCT Lentiviral Activation Particles (h) - sc-401920-LAC from Santa Cruz Biotechnology
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xCT Lentiviral Activation Particles (h2) - sc-401920-LAC-2 from Santa Cruz Biotechnology
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xCT siRNA (h) - sc-76933 from Santa Cruz Biotechnology
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xCT shRNA Plasmid (h) - sc-76933-SH from Santa Cruz Biotechnology
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xCT shRNA (h) Lentiviral Particles - sc-76933-V from Santa Cruz Biotechnology
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xCT RNAi - H00023657-R01 from Novus Biologicals
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MISSION® esiRNA - EHU070231 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2395 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2395 from Sigma-Aldrich
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SLC7A11 siRNA (Human) - CRH8426 from Cohesion Biosciences
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SLC7A11 - MBS8204217 from MyBioSource
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xCT CRISPR/Cas9 KO Plasmid (h2) - sc-401920-KO-2 from Santa Cruz Biotechnology
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xCT HDR Plasmid (h2) - sc-401920-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human SLC7A11 (NM_014331.3) - SHH412056 from Creative biogene
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shRNA set against Human SLC7A11(NM_014331.3) - SHL011790 from Creative biogene
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SLC7A11 shRNA Plasmid (Human) - CHH8426 from Cohesion Biosciences
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SLC7A11 miRNA 3'UTR clone - MiUTR1H-09597 from Creative biogene
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