| Gene Symbol |
DYNC1LI2
|
| Entrez Gene |
1783
|
| Alt Symbol |
DNCLI2, LIC2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
dynein, cytoplasmic 1, light intermediate chain 2
|
| Other Description |
LIC-2|LIC53/55|cytoplasmic dynein 1 light intermediate chain 2|dynein light intermediate chain 2, cytosolic|dynein, cytoplasmic, light intermediate polypeptide 2
|
| Swissprots |
A8K6V1 B4DZP4 Q8TAT3 O43237
|
| Accessions |
EAW83039 EAW83040 O43237 AF035812 AAB88513 AK024863 AK095237 AK291766 BAF84455 AK295049 BAG58099 AK303031 BAG64156 AK304233 BAG65102 AL708642 BC010928 BC022934 BC025959 AAH25959 BC036633 BC069056 BM805417 BX648863 CAH56157 XR_933225 NM_001286157 NP_001273086 NM_006141 NP_006132
|
| Function |
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
|
| Subcellular Location |
Cytoplasm, cytoskeleton {ECO:0000250}.
|
| Top Pathways |
Vasopressin-regulated water reabsorption, Phagosome, Salmonella infection
|