| Gene Symbol | SNAP29 |
|---|---|
| Entrez Gene | 9342 |
| Alt Symbol | CEDNIK, SNAP-29 |
| Species | Human |
| Gene Type | protein-coding |
| Description | synaptosomal-associated protein, 29kDa |
| Other Description | soluble 29 kDa NSF attachment protein|synaptosomal-associated protein 29|synaptosomal-associated protein, 29kD|vesicle-membrane fusion protein SNAP-29 |
| Swissprots | O95721 |
| Accessions | AAF91421 EAX02935 O95721 AF115436 AAD11436 AK024704 BC009715 AAH09715 BF435261 BG773022 BT007357 AAP36021 CA427899 CR456582 CAG30468 CU013181 CAK54612 CU013469 CAK54911 NM_004782 NP_004773 |
| Function | SNAREs, Soluble N-ethylmaleimide-sensitive factor- attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Probably involved in multiple membrane trafficking steps. {ECO:0000269|PubMed:23217709}. |
| Subcellular Location | Cytoplasm. Membrane; Peripheral membrane protein. Cell junction, synapse, synaptosome. Note=Appears to be mostly membrane-bound, probably via interaction with syntaxins, but a significant portion is cytoplasmic. |
| Tissue Specificity | Found in brain, heart, kidney, liver, lung, placenta, skeletal muscle, spleen and pancreas. |
| Top Pathways | SNARE interactions in vesicular transport |