Gene Symbol | SNAP29 |
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Entrez Gene | 9342 |
Alt Symbol | CEDNIK, SNAP-29 |
Species | Human |
Gene Type | protein-coding |
Description | synaptosomal-associated protein, 29kDa |
Other Description | soluble 29 kDa NSF attachment protein|synaptosomal-associated protein 29|synaptosomal-associated protein, 29kD|vesicle-membrane fusion protein SNAP-29 |
Swissprots | O95721 |
Accessions | AAF91421 EAX02935 O95721 AF115436 AAD11436 AK024704 BC009715 AAH09715 BF435261 BG773022 BT007357 AAP36021 CA427899 CR456582 CAG30468 CU013181 CAK54612 CU013469 CAK54911 NM_004782 NP_004773 |
Function | SNAREs, Soluble N-ethylmaleimide-sensitive factor- attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Probably involved in multiple membrane trafficking steps. {ECO:0000269|PubMed:23217709}. |
Subcellular Location | Cytoplasm. Membrane; Peripheral membrane protein. Cell junction, synapse, synaptosome. Note=Appears to be mostly membrane-bound, probably via interaction with syntaxins, but a significant portion is cytoplasmic. |
Tissue Specificity | Found in brain, heart, kidney, liver, lung, placenta, skeletal muscle, spleen and pancreas. |
Top Pathways | SNARE interactions in vesicular transport |
SNAP 29 CRISPR/Cas9 KO Plasmid (h) - sc-409739 from Santa Cruz Biotechnology
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SNAP 29 HDR Plasmid (h) - sc-409739-HDR from Santa Cruz Biotechnology
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SNAP 29 Double Nickase Plasmid (h) - sc-409739-NIC from Santa Cruz Biotechnology
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SNAP 29 Double Nickase Plasmid (h2) - sc-409739-NIC-2 from Santa Cruz Biotechnology
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SNAP 29 CRISPR Activation Plasmid (h) - sc-409739-ACT from Santa Cruz Biotechnology
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SNAP 29 CRISPR Activation Plasmid (h2) - sc-409739-ACT-2 from Santa Cruz Biotechnology
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SNAP 29 Lentiviral Activation Particles (h) - sc-409739-LAC from Santa Cruz Biotechnology
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SNAP 29 Lentiviral Activation Particles (h2) - sc-409739-LAC-2 from Santa Cruz Biotechnology
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SNAP 29 siRNA (h) - sc-76531 from Santa Cruz Biotechnology
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SNAP 29 shRNA Plasmid (h) - sc-76531-SH from Santa Cruz Biotechnology
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SNAP 29 shRNA (h) Lentiviral Particles - sc-76531-V from Santa Cruz Biotechnology
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SNAP29 RNAi - H00009342-R01 from Novus Biologicals
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MISSION® esiRNA - EHU013181 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19823 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19823 from Sigma-Aldrich
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SNAP29 siRNA (Human) - CRH6183 from Cohesion Biosciences
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SNAP29 - MBS8240093 from MyBioSource
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shRNA set against Human SNAP29 (NM_004782.3) - SHH413884 from Creative biogene
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SNAP29 shRNA Plasmid (Human) - CHH6183 from Cohesion Biosciences
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SNAP29 miRNA 3'UTR clone - MiUTR4H-TG08354 from Creative biogene
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