| Gene Symbol |
SNAP29
|
| Entrez Gene |
9342
|
| Alt Symbol |
CEDNIK, SNAP-29
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
synaptosomal-associated protein, 29kDa
|
| Other Description |
soluble 29 kDa NSF attachment protein|synaptosomal-associated protein 29|synaptosomal-associated protein, 29kD|vesicle-membrane fusion protein SNAP-29
|
| Swissprots |
O95721
|
| Accessions |
AAF91421 EAX02935 O95721 AF115436 AAD11436 AK024704 BC009715 AAH09715 BF435261 BG773022 BT007357 AAP36021 CA427899 CR456582 CAG30468 CU013181 CAK54612 CU013469 CAK54911 NM_004782 NP_004773
|
| Function |
SNAREs, Soluble N-ethylmaleimide-sensitive factor- attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Probably involved in multiple membrane trafficking steps. {ECO:0000269|PubMed:23217709}.
|
| Subcellular Location |
Cytoplasm. Membrane; Peripheral membrane protein. Cell junction, synapse, synaptosome. Note=Appears to be mostly membrane-bound, probably via interaction with syntaxins, but a significant portion is cytoplasmic.
|
| Tissue Specificity |
Found in brain, heart, kidney, liver, lung, placenta, skeletal muscle, spleen and pancreas.
|
| Top Pathways |
SNARE interactions in vesicular transport
|
![Western Blot: SNAP29 Overexpression Lysate (Adult Normal) [NBP2-04278] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SNAP29.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4128_SNAP29%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-04278-img0001.jpg)