Gene Symbol | PKP1 |
---|---|
Entrez Gene | 5317 |
Alt Symbol | B6P |
Species | Human |
Gene Type | protein-coding |
Description | plakophilin 1 |
Other Description | band 6 protein|plakophilin-1 |
Swissprots | Q13835 Q15152 O00645 Q14CA0 |
Accessions | CAA98022 CAP07488 CAP07489 CAP11456 CAP11457 CAR97070 CAR97071 CAT82292 CAT82293 EAW91350 EAW91351 EAW91352 Q13835 AK123555 AK299473 BAG61437 AK315291 AK316131 BAH14502 BC040253 BC114571 AAI14572 BC115702 AAI15703 X79293 CAA55881 Z34974 CAA84426 NM_000299 NP_000290 NM_001005337 NP_001005337 |
Function | Seems to play a role in junctional plaques. Contributes to epidermal morphogenesis. {ECO:0000269|PubMed:9326952}. |
Subcellular Location | Isoform 1: Nucleus. Cell junction, desmosome. |
Tissue Specificity | Isoform 2 is widely expressed. Isoform 1 is expressed in stratified squamous, complex, glandular duct and bladder epithelia. |