Gene Symbol | PKP1 |
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Entrez Gene | 5317 |
Alt Symbol | B6P |
Species | Human |
Gene Type | protein-coding |
Description | plakophilin 1 |
Other Description | band 6 protein|plakophilin-1 |
Swissprots | Q13835 Q15152 O00645 Q14CA0 |
Accessions | CAA98022 CAP07488 CAP07489 CAP11456 CAP11457 CAR97070 CAR97071 CAT82292 CAT82293 EAW91350 EAW91351 EAW91352 Q13835 AK123555 AK299473 BAG61437 AK315291 AK316131 BAH14502 BC040253 BC114571 AAI14572 BC115702 AAI15703 X79293 CAA55881 Z34974 CAA84426 NM_000299 NP_000290 NM_001005337 NP_001005337 |
Function | Seems to play a role in junctional plaques. Contributes to epidermal morphogenesis. {ECO:0000269|PubMed:9326952}. |
Subcellular Location | Isoform 1: Nucleus. Cell junction, desmosome. |
Tissue Specificity | Isoform 2 is widely expressed. Isoform 1 is expressed in stratified squamous, complex, glandular duct and bladder epithelia. |
plakophilin 1 CRISPR/Cas9 KO Plasmid (h) - sc-403577 from Santa Cruz Biotechnology
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plakophilin 1 HDR Plasmid (h) - sc-403577-HDR from Santa Cruz Biotechnology
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plakophilin 1 Double Nickase Plasmid (h) - sc-403577-NIC from Santa Cruz Biotechnology
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plakophilin 1 Double Nickase Plasmid (h2) - sc-403577-NIC-2 from Santa Cruz Biotechnology
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plakophilin 1 CRISPR Activation Plasmid (h) - sc-403577-ACT from Santa Cruz Biotechnology
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plakophilin 1 CRISPR Activation Plasmid (h2) - sc-403577-ACT-2 from Santa Cruz Biotechnology
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plakophilin 1 Lentiviral Activation Particles (h) - sc-403577-LAC from Santa Cruz Biotechnology
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plakophilin 1 Lentiviral Activation Particles (h2) - sc-403577-LAC-2 from Santa Cruz Biotechnology
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plakophilin 1 siRNA (h) - sc-43180 from Santa Cruz Biotechnology
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plakophilin 1 shRNA Plasmid (h) - sc-43180-SH from Santa Cruz Biotechnology
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plakophilin 1 shRNA (h) Lentiviral Particles - sc-43180-V from Santa Cruz Biotechnology
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Plakophilin 1 RNAi - H00005317-R02 from Novus Biologicals
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Plakophilin 1 RNAi - H00005317-R01 from Novus Biologicals
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MISSION® esiRNA - EHU068941 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16876 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16876 from Sigma-Aldrich
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PKP1 siRNA (Human) - CRH3558 from Cohesion Biosciences
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shRNA set against Human PKP1 (NM_000299.3) - SHH376596 from Creative biogene
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Human PKP1 siRNA - orb264060 from Biorbyt
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PKP1 shRNA Plasmid (Human) - CHH3558 from Cohesion Biosciences
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PKP1 miRNA 3'UTR clone - MiUTR4H-TG06731 from Creative biogene
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