| Gene Symbol |
PLEKHG2
|
| Entrez Gene |
64857
|
| Alt Symbol |
ARHGEF42, CLG
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
|
| Other Description |
CTB-60E11.4|PH domain-containing family G member 2|common-site lymphoma/leukemia guanine nucleotide exchange factor|pleckstrin homology domain-containing family G member 2
|
| Swissprots |
Q96BU2 Q9H699 Q96D18 B8ZZK6 Q9H7P9 Q6DHV6 C9J0Y4
|
| Accessions |
EAW56887 EAW56888 EAW56889 EAW56890 EAW56891 Q9H7P9 AK024429 BAB15719 AK026111 BAB15364 AK095957 AK302476 BAG63764 AL832850 BC013426 AAH13426 BC015174 AAH15174 BC075858 AAH75858 XM_005259163 XP_005259220 XM_006723332 XP_006723395 XM_006723333 XP_006723396 XM_006723334 XP_006723397 XM_011527231 XP_011525533 XM_011527232 XP_011525534 XM_011527233 XP_011525535 XM_011527234 XP_011525536 NM_022835 NP_073746
|
| Function |
May be a transforming oncogene with exchange activity for CDC42 (By similarity). May be a guanine-nucleotide exchange factor (GEF) for RAC1 and CDC42. Activated by the binding to subunits beta and gamma of the heterotrimeric guanine nucleotide- binding protein (G protein). {ECO:0000250, ECO:0000269|PubMed:18045877}.
|