Gene Symbol | PLEKHG2 |
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Entrez Gene | 64857 |
Alt Symbol | ARHGEF42, CLG |
Species | Human |
Gene Type | protein-coding |
Description | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 |
Other Description | CTB-60E11.4|PH domain-containing family G member 2|common-site lymphoma/leukemia guanine nucleotide exchange factor|pleckstrin homology domain-containing family G member 2 |
Swissprots | Q96BU2 Q9H699 Q96D18 B8ZZK6 Q9H7P9 Q6DHV6 C9J0Y4 |
Accessions | EAW56887 EAW56888 EAW56889 EAW56890 EAW56891 Q9H7P9 AK024429 BAB15719 AK026111 BAB15364 AK095957 AK302476 BAG63764 AL832850 BC013426 AAH13426 BC015174 AAH15174 BC075858 AAH75858 XM_005259163 XP_005259220 XM_006723332 XP_006723395 XM_006723333 XP_006723396 XM_006723334 XP_006723397 XM_011527231 XP_011525533 XM_011527232 XP_011525534 XM_011527233 XP_011525535 XM_011527234 XP_011525536 NM_022835 NP_073746 |
Function | May be a transforming oncogene with exchange activity for CDC42 (By similarity). May be a guanine-nucleotide exchange factor (GEF) for RAC1 and CDC42. Activated by the binding to subunits beta and gamma of the heterotrimeric guanine nucleotide- binding protein (G protein). {ECO:0000250, ECO:0000269|PubMed:18045877}. |
PLEKHG2 CRISPR/Cas9 KO Plasmid (h) - sc-413048 from Santa Cruz Biotechnology
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PLEKHG2 HDR Plasmid (h) - sc-413048-HDR from Santa Cruz Biotechnology
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PLEKHG2 Double Nickase Plasmid (h) - sc-413048-NIC from Santa Cruz Biotechnology
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PLEKHG2 Double Nickase Plasmid (h2) - sc-413048-NIC-2 from Santa Cruz Biotechnology
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PLEKHG2 CRISPR Activation Plasmid (h) - sc-413048-ACT from Santa Cruz Biotechnology
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PLEKHG2 CRISPR Activation Plasmid (h2) - sc-413048-ACT-2 from Santa Cruz Biotechnology
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PLEKHG2 Lentiviral Activation Particles (h) - sc-413048-LAC from Santa Cruz Biotechnology
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PLEKHG2 Lentiviral Activation Particles (h2) - sc-413048-LAC-2 from Santa Cruz Biotechnology
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PLEKHG2 siRNA (h) - sc-97423 from Santa Cruz Biotechnology
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PLEKHG2 shRNA Plasmid (h) - sc-97423-SH from Santa Cruz Biotechnology
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PLEKHG2 shRNA (h) Lentiviral Particles - sc-97423-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU013311 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16960 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16960 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01477 from Sigma-Aldrich
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PLEKHG2 siRNA (Human) - CRJ2124 from Cohesion Biosciences
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shRNA set against Human PLEKHG2 (NM_022835.2) - SHH377616 from Creative biogene
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shRNA set against Human PLEKHG2(NM_022835.2) - SHR122250 from Creative biogene
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Human PLEKHG2 siRNA - orb272625 from Biorbyt
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PLEKHG2 shRNA Plasmid (Human) - CHJ2124 from Cohesion Biosciences
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PLEKHG2 miRNA 3'UTR clone - MiUTR1H-08000 from Creative biogene
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