Gene Symbol | SYT11 |
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Entrez Gene | 23208 |
Alt Symbol | SYT12, sytXI |
Species | Human |
Gene Type | protein-coding |
Description | synaptotagmin XI |
Other Description | synaptotagmin 12|synaptotagmin-11 |
Swissprots | Q9BT88 Q5W0D4 Q96SU2 Q8IXU3 Q68CT5 Q14998 |
Accessions | EAW53025 EAW53026 Q9BT88 AA824539 AK026178 AK027540 BAB55186 AK074931 BAC11300 AK296378 BAG59052 AU130124 BC004291 AAH04291 BC013690 AAH13690 BC039205 AAH39205 BM801649 CA419920 CR749792 CAH18653 D38522 BAA07527 DA026743 DA239014 XM_005245014 XP_005245071 NM_152280 NP_689493 |
Function | May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. {ECO:0000250}. |
Subcellular Location | Membrane {ECO:0000269|PubMed:12925569}; Single-pass membrane protein {ECO:0000269|PubMed:12925569}. Cell junction, synapse {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Note=In substantia nigra, observed in neuronal cell bodies and neurites. Found in the core of the Lewy bodies in the brain of sporadic Parkinson disease patients. |
Synaptotagmin XI CRISPR/Cas9 KO Plasmid (h) - sc-404323 from Santa Cruz Biotechnology
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Synaptotagmin XI HDR Plasmid (h) - sc-404323-HDR from Santa Cruz Biotechnology
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Synaptotagmin XI Double Nickase Plasmid (h) - sc-404323-NIC from Santa Cruz Biotechnology
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Synaptotagmin XI Double Nickase Plasmid (h2) - sc-404323-NIC-2 from Santa Cruz Biotechnology
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Synaptotagmin XI CRISPR Activation Plasmid (h) - sc-404323-ACT from Santa Cruz Biotechnology
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Synaptotagmin XI CRISPR Activation Plasmid (h2) - sc-404323-ACT-2 from Santa Cruz Biotechnology
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Synaptotagmin XI Lentiviral Activation Particles (h) - sc-404323-LAC from Santa Cruz Biotechnology
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Synaptotagmin XI Lentiviral Activation Particles (h2) - sc-404323-LAC-2 from Santa Cruz Biotechnology
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Synaptotagmin XI siRNA (h) - sc-88813 from Santa Cruz Biotechnology
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Synaptotagmin XI shRNA Plasmid (h) - sc-88813-SH from Santa Cruz Biotechnology
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Synaptotagmin XI shRNA (h) Lentiviral Particles - sc-88813-V from Santa Cruz Biotechnology
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Synaptotagmin 12 RNAi - H00091683-R01 from Novus Biologicals
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SYT11 RNAi - H00023208-R01 from Novus Biologicals
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MISSION® esiRNA - EHU028451 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20914 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20914 from Sigma-Aldrich
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SYT11 siRNA (Human) - CRH8086 from Cohesion Biosciences
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SYT11 - MBS8227865 from MyBioSource
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shRNA set against Human SYT11 (NM_152280.4) - SHH421940 from Creative biogene
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Human SYT11 siRNA - orb268588 from Biorbyt
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SYT11 shRNA Plasmid (Human) - CHH8086 from Cohesion Biosciences
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SYT11 miRNA 3'UTR clone - MiUTR4H-TG08713 from Creative biogene
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