Gene Symbol | ZNF282 |
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Entrez Gene | 8427 |
Alt Symbol | HUB1 |
Species | Human |
Gene Type | protein-coding |
Description | zinc finger protein 282 |
Other Description | HTLV-I U5 repressive element-binding protein 1|HTLV-I U5RE-binding protein 1|HUB-1 |
Swissprots | Q6DKK0 O43691 B4DRI5 Q9UDV7 |
Accessions | EAL24430 EAW80055 EAW80056 Q9UDV7 AK299280 BAG61297 AK316282 BAH14653 AY927504 AY927505 BC009542 BC031686 AAH31686 BC041704 AAH41704 BC055287 AAH55287 BC073805 AAH73805 BU731447 CV573257 D30612 BAA24380 XM_006716151 XP_006716214 XM_011516628 XP_011514930 NM_001303481 NP_001290410 NM_003575 NP_003566 |
Function | Binds to the U5 repressive element (U5RE) of the human T cell leukemia virus type I long terminal repeat. It recognizes the 5'-TCCACCCC-3' sequence as a core motif and exerts a strong repressive effect on HTLV-I LTR-mediated expression. |
Subcellular Location | Nucleus {ECO:0000305}. |
Tissue Specificity | Ubiquitous. |
ZNF282 CRISPR/Cas9 KO Plasmid (h) - sc-409149 from Santa Cruz Biotechnology
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ZNF282 HDR Plasmid (h) - sc-409149-HDR from Santa Cruz Biotechnology
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ZNF282 Double Nickase Plasmid (h) - sc-409149-NIC from Santa Cruz Biotechnology
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ZNF282 Double Nickase Plasmid (h2) - sc-409149-NIC-2 from Santa Cruz Biotechnology
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ZNF282 CRISPR Activation Plasmid (h) - sc-409149-ACT from Santa Cruz Biotechnology
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ZNF282 CRISPR Activation Plasmid (h2) - sc-409149-ACT-2 from Santa Cruz Biotechnology
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ZNF282 Lentiviral Activation Particles (h) - sc-409149-LAC from Santa Cruz Biotechnology
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ZNF282 Lentiviral Activation Particles (h2) - sc-409149-LAC-2 from Santa Cruz Biotechnology
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ZNF282 siRNA (h) - sc-89572 from Santa Cruz Biotechnology
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ZNF282 shRNA Plasmid (h) - sc-89572-SH from Santa Cruz Biotechnology
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ZNF282 shRNA (h) Lentiviral Particles - sc-89572-V from Santa Cruz Biotechnology
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ZNF282 RNAi - H00008427-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN23362 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23362 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12703 from Sigma-Aldrich
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ZNF282 siRNA (Human) - CRH5520 from Cohesion Biosciences
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ZNF282 - MBS8209732 from MyBioSource
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shRNA set against Human ZNF282 (NM_003575.2) - SHH453532 from Creative biogene
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ZNF282 shRNA Plasmid (Human) - CHH5520 from Cohesion Biosciences
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ZNF282 miRNA 3'UTR clone - MiUTR1H-11546 from Creative biogene
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