| Gene Symbol |
ORAI2
|
| Entrez Gene |
80228
|
| Alt Symbol |
C7orf19, CBCIP2, MEM142B, TMEM142B
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ORAI calcium release-activated calcium modulator 2
|
| Other Description |
CAP-binding protein complex interacting protein 2|CAP-binding protein complex-interacting protein 2|H_NH0514P08.8|protein orai-2|putative protein ORAI2-2|transmembrane protein 142B
|
| Swissprots |
Q9H9Y3 Q6IA68 Q96SN7 Q8WY94
|
| Accessions |
AAP22351 AAP22352 EAW50244 EAW50245 EAW50246 EAW50247 EAW50248 Q96SN7 AF258552 AAG23755 AK022536 AK027639 BAB55256 AK056497 AK128753 AK300574 BAG62276 BC009183 BC016797 BC069270 AAH69270 CN366874 CR457287 CAG33568 DA770788 DC384892 HY064081 Y10777 NM_001126340 NP_001119812 NM_001271818 NP_001258747 NM_001271819 NP_001258748 NM_032831 NP_116220
|
| Function |
Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase in Ca(2+)- selective current by synergy with the Ca(2+) sensor, STIM1. {ECO:0000269|PubMed:16807233, ECO:0000269|PubMed:17452328}.
|
| Subcellular Location |
Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
| Top Pathways |
Calcium signaling pathway
|