Gene Symbol | ORAI2 |
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Entrez Gene | 80228 |
Alt Symbol | C7orf19, CBCIP2, MEM142B, TMEM142B |
Species | Human |
Gene Type | protein-coding |
Description | ORAI calcium release-activated calcium modulator 2 |
Other Description | CAP-binding protein complex interacting protein 2|CAP-binding protein complex-interacting protein 2|H_NH0514P08.8|protein orai-2|putative protein ORAI2-2|transmembrane protein 142B |
Swissprots | Q9H9Y3 Q6IA68 Q96SN7 Q8WY94 |
Accessions | AAP22351 AAP22352 EAW50244 EAW50245 EAW50246 EAW50247 EAW50248 Q96SN7 AF258552 AAG23755 AK022536 AK027639 BAB55256 AK056497 AK128753 AK300574 BAG62276 BC009183 BC016797 BC069270 AAH69270 CN366874 CR457287 CAG33568 DA770788 DC384892 HY064081 Y10777 NM_001126340 NP_001119812 NM_001271818 NP_001258747 NM_001271819 NP_001258748 NM_032831 NP_116220 |
Function | Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase in Ca(2+)- selective current by synergy with the Ca(2+) sensor, STIM1. {ECO:0000269|PubMed:16807233, ECO:0000269|PubMed:17452328}. |
Subcellular Location | Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Top Pathways | Calcium signaling pathway |
Orai2 CRISPR/Cas9 KO Plasmid (h) - sc-403535 from Santa Cruz Biotechnology
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Orai2 HDR Plasmid (h) - sc-403535-HDR from Santa Cruz Biotechnology
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Orai2 Double Nickase Plasmid (h) - sc-403535-NIC from Santa Cruz Biotechnology
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Orai2 Double Nickase Plasmid (h2) - sc-403535-NIC-2 from Santa Cruz Biotechnology
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Orai2 CRISPR Activation Plasmid (h) - sc-403535-ACT from Santa Cruz Biotechnology
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Orai2 CRISPR Activation Plasmid (h2) - sc-403535-ACT-2 from Santa Cruz Biotechnology
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Orai2 Lentiviral Activation Particles (h) - sc-403535-LAC from Santa Cruz Biotechnology
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Orai2 Lentiviral Activation Particles (h2) - sc-403535-LAC-2 from Santa Cruz Biotechnology
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Orai2 siRNA (h) - sc-76003 from Santa Cruz Biotechnology
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Orai2 shRNA Plasmid (h) - sc-76003-SH from Santa Cruz Biotechnology
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Orai2 shRNA (h) Lentiviral Particles - sc-76003-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU060251 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16140 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16140 from Sigma-Aldrich
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ORAI2 siRNA (Human) - CRJ2816 from Cohesion Biosciences
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shRNA set against Human ORAI2 (NM_032831.2) - SHH368360 from Creative biogene
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Human ORAI2 siRNA - orb273317 from Biorbyt
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ORAI2 shRNA Plasmid (Human) - CHJ2816 from Cohesion Biosciences
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