| Gene Symbol |
APOOL
|
| Entrez Gene |
139322
|
| Alt Symbol |
CXorf33, FAM121A, UNQ8193
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
apolipoprotein O-like
|
| Other Description |
AAIR8193|MICOS complex subunit MIC27|family with sequence similarity 121A
|
| Swissprots |
Q6UXV4 Q5H9D1 Q3KNU7
|
| Accessions |
EAW98568 Q6UXV4 AK096909 AK130506 AY358193 AAQ88560 BC107095 BC107096 AAI07097 BE328646 BI038188 CR749250 CAH18106 XM_011530859 XP_011529161 XM_011530860 XP_011529162 XM_011530861 XP_011529163 NM_198450 NP_940852
|
| Function |
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Specifically binds to cardiolipin (in vitro) but not to the precursor lipid phosphatidylglycerol. {ECO:0000269|PubMed:23704930}.
|
| Subcellular Location |
Mitochondrion inner membrane {ECO:0000269|PubMed:23704930}; Multi-pass membrane protein {ECO:0000269|PubMed:23704930}.
|