Gene Symbol | ANXA1 |
---|---|
Entrez Gene | 301 |
Alt Symbol | ANX1, LPC1 |
Species | Human |
Gene Type | protein-coding |
Description | annexin A1 |
Other Description | annexin I (lipocortin I)|annexin-1|calpactin II|calpactin-2|chromobindin-9|phospholipase A2 inhibitory protein |
Swissprots | P04083 |
Accessions | ADZ76495 EAW62545 EAW62546 EAW62547 EAW62548 EAW62549 EAW62550 P04083 AA039737 AB451274 BAG70088 AB451401 BAG70215 AK074480 AK296808 BAG59381 AK311684 BC001275 AAH01275 BC018683 BC034157 AAH34157 BC035993 AAH35993 BT019896 AAV38699 BT019916 AAV38719 BT019917 AAV38720 CR407684 CAG28612 CX870105 DQ891173 ABM82099 DQ894338 ABM85264 X05908 CAA29338 XM_011518608 XP_011516910 XM_011518609 XP_011516911 NM_000700 NP_000691 |
Function | Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity. |
Subcellular Location | Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Cell projection, cilium {ECO:0000250}. Basolateral cell membrane {ECO:0000250}. Note=Found in the cilium, nucleus and basolateral cell membrane of ciliated cells in the tracheal endothelium. Found in the cytoplasm of type II pneumocytes and alveolar macrophages. {ECO:0000250}. |